Ladies, 2 months ago I had my first bad pap reading "LSIL/hrHPV/CIN 1." A month later I had a satisfactory colposcopy and two biopsies from the same 1:00 lesion.

I received my biopsy report today, and I'm very confused. Obviously, I am going to inquire further at my follow-up, but it's not for a few months. I would appreciate any input interpreting this. It reads as follows:

Diagnosis:
1. (cervical biopsy 1:00) CIN 1
2. (ECC) benign endocervical curettings

However, under "microscopic descriptions" for each, it reads:

1. (cervical biopsy) sections consist of fragments of metaplastic and inflamed endocervical mucosa with koilocytotic atypia.
2. (ECC) sections consist of blood, mucus, and scanty benign endocervical cells.

I know koilocytotic changes mean hpv is causing nuclear changes in cells. My concern is WHERE the koilocytotic changes are being found. If the cervical biopsies are by definition exocervical (outside the canal), why does it then discuss endocervical mucosa? Does this mean there IS ECC involvement (contrary to the curettage report) that is not quite dysplastic yet, but showing definite signs of hpv infection?

Or, is this "gland duct" involvement? (But I thought that was almost always associated with CIN 2-3?)

Or, is this the precursor to AIS? (adenocarcinoma in situ)

Is gland duct involvement the same as pre-AIS?

Also, why is there no mention of dysplasia in the description (just "metaplasia"), yet the diagnosis says CIN 1 which is clearly dysplastic?

I would really appreciate if someone well-versed could shed light on the above. I'm trying not to make too much of it until my followup, but the conflicting info on exo/endo is a bit troubling.

Many Thanks.

You may have had your follow up already, but if not call and make an appointment to go over the results, take a list of your questions and take someone with you- 2 sets of ears is always better.
AIS- IF you had it or getting it you wouldn't be waiting - its rare and it is glandular and its deadly more so than squanom cell - as well it isn't so much traceable with a PAP. A pap tests the outer cells, not the inner cells. 6 yrs from AIS diagnosis PAP was returned negative 10 days prior to my diagnoses of AIS from a biopsy because the tumor was growing out and it could be seen. So PAPs are great but they don't detect everything.
It is important to be educated. Ask your DR only they can explain.
Remember no matter what, you control how you go through this. and sometimes we can't stop cancer from being there but we can sure fight it if we are educated and honest about our bodies. So good luck.

Snobun1, thanks for your response, and I am so sorry about what you went through. I hope you're ok now. My gyn-onc never called me, so I'm just going to wait for my followup in 2 months.