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View Full Version : My son's labs...13 years old


teresa0328
02-12-2008, 06:48 PM
My son has had a few hypoglycemic episodes. That led us to see an endo. He's had a 24 hr urine & blood tests. After the 1st results, the endo had him redo this. We get those results on Thursday.
Here's the some of the 1st labs with ranges in ( ):
Sodium 140 (132-143)
Potassium 5.2 H ( 3.6-5.1)
ACTH 18 (0-46)
Cortisol (AM) 5.0 L (6-28)
Urinary Free Cortisol 24 hour:
Creat, UR 47 mg/dl
Creat, UR 893 mg/day
Cortisol, free 4.7 (2.1-38) ug/day
Cortisol, free 2.47 ug/L

Does this give any indication of addison's or hypopit.?
I'm concerned that we are going through a 2 week process on this. Is he does have addison's do these labs show he needs any meds?
Thanks!

rumpled
02-13-2008, 12:29 PM
He does look lowish on the cortisol side so the doctor should send him for an ACTH stim test to make a clear diagnosis. The high potassium is a sign that things may need to be watched but his sodium was good - usually an addisonian crisis occurs when potassium spikes and sodium drops. If he does not pass the stimulation test, then he will need to be on a replacement steroid, usually for life. Depending on the doctor's preference, it is usually hydrocortosone or prednisone. Hydocortisone is preferable, in my opinion, as it more closely mimics the body, is shorter acting, and gives the body the overnight break it usually gets to more closely mimic a natural diurnal rhythm. Often, prednisone is given for once a day dosing but it is a long acting steroid and does not give the body a break. More side effects such as bone necrosis, streoid myopathy and cataracts may happen later from it. Thankfully, there is a new drug that is getting approval which is a short acting steroid that is once a day dosing and minics the body's diurnal rythym. Too little steroid is bad, and too much will give you Cushing's disease which is also harmful to your health. It is important to give just enough.

As for hypopit, you did not post enough tests to determine that - only ACTH was pituitary. No other pituitary hormone was posted - LH, FSH, TSH, GH (usually IGF-1 is more reliable), Vasopressen are pituitary hormones.

teresa0328
02-13-2008, 12:52 PM
I don't have the other labs with me...but I don't remember any other labs that were out of range. So maybe this is a good sign. Thank you very much for your reply.

 
 
 




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