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View Full Version : Yet Another HCV Drug?


LOST1
12-11-2002, 12:44 PM
Howdy-

Another HCV drug being tested
AVI BioPharma, Inc. today announced promising preclinical results from targeting single stranded RNA viruses with its proprietary NEUGENE(R) antisense drugs, I believe it is based in Israel.

The viral program, , has focused primarily on one family of viruses that includes West Nile virus, hepatitis C virus (HCV) and Calicivirus.

Some quotes- "The significant amount of attention now being focused on viruses in our environment, both naturally occurring viruses, and those with the potential for being used in biological warfare, parallels AVI's ongoing emphasis on the use of NEUGENE antisense compounds as antiviral drugs,". "We've seen encouraging results in studies on three similar viruses including West Nile virus, HCV and Calicivirus.

AVI recently treated a group of three Humboldt penguins at the Milwaukee County Zoo suffering from a natural outbreak of West Nile virus. The study tested the hypothesis that NEUGENE antisense drugs targeting West Nile virus will be effective against the infection. All three penguins have lived for over one-and-a-half months since treatment.

This positive outcome differed from that of 10 flockmates who died from West Nile virus at the same zoo,, the NEUGENE-treated penguins survived and the characteristic weight loss from the virus was blocked.

West Nile virus is spread by the bite of an infected mosquito, and can infect people, horses, many types of birds and some other animals. West Nile virus infection can result in severe and sometimes fatal illnesses, makes you wonder if HCV will or can ever be passed by an mosquito also.

AVI plans to initiate clinical trials against HCV in 2003.
Hepatitis C virus (HCV) is a single-stranded RNA virus like West Nile virus so these tests are encouraging, we are seeing almost a race now for a cure for HCV, gotta like that.
Be well-



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--Get Outdoors-Enjoy Life----Neil

 
 
 




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