Wondering if anyone is taking Niaspan. My doctor does not want me to take it. But I can't handle the side effects of statins anymore. I can live flushing from Niacin over the fatigue and muscle aches of statins. Any other side effects of Niaspan that anyone has experienced? Also is time released Niacin from GNC compareable to Niaspan?

Hi,
I just started taking Niaspan. Last night was my first dose. I did get a slight flushing feeling, nothing to bad. I'll have to wait and see.
Why doesn't your doctor want you to take the Niaspan?

I had started off on Baycol did fantastic on it. Of course stopped once it was pulled from the market. They then put me on Zocor and it made me achy, so I stopped taking it myself.

I did read some post others wrote on Niaspan/Niacin. You can find it in past post. Pretty informative.

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If it weren't for the BRAVE there would be no land of the FREE!!

I have been on Niaspan since late 1997. My results have been great. I had flushing in the beginning but it went away with time. Look for the board "Niaspan makes me smile" on page 2. Do not take the time release niacin. It is dangerous. See the following.

<Studies in hyperlipidemic patients have been conducted with a number of SR nicotinic acid products. These studies have demonstrated that the sustained release products do not have the same advantageous lipid altering effects as IR nicotinic acid, and in fact often have a worse side effect profile compared to the IR products. The major disadvantage of the SR formulations, as can be seen in Knopp et al., in 1985, is the significantly lower reduction in triglycerides (-2% for the sustained versus -38% for the immediate release) and lower increase in HDL cholesterol, represented as HDL2 particles which are known by the art to be most beneficial, (-5% for the sustained release versus +37/% for the immediate release).

Additionally, SR nicotinic acid formulations have been noted as causing greater incidences of liver toxicity as described in Henken et al.: Am J Med, 91:1991 (1991) and Dalton et al.: Am J Med, 93:102 (1992). There is also great concern regarding the potential of these formulations in disrupting glucose metabolism and uric acid levels.

In a recent edition of the Journal of the American Medical Association, an article appeared which presented research results investigating the liver toxicity problems associated with an SR form of nicotinic acid. See McKenney et al.: A Comparison of the Efficacy and Toxic Effects of Sustained- vs. Immediate-Release Niacin in Hypercholesterolemic Patients, JAMA, (271)9: 672 (Mar. 2, 1994). This McKenney et al. article presented a study of twenty-three patients. Of that number, 18 or 78 percent were forced to withdraw because liver function tests (FTs) increased indicating potential liver damage. The conclusion of the authors of that article was that the SR form of nicotinic acid "should be restricted from use."

A similar conclusion was reached in an article authored by representatives of the Food and Drug Administration. See Radar, et al.: Hepatic Toxicity of Unmodified and Time-Release Preparations of Niacin, JAMA, 92:77 (January 1992). Because of these studies and similar conclusions drawn by other health care professionals, the sustained release forms of nicotinic acid have experienced limited utilization.>

Much more information on Niaspan Makes Me Smile.

bob

rstarre,

Was there any specific reason given as to why your doctor does not want you to take niacin?