i have a jpouch. had it since 2004. i took acyclovir for genital herpes for 10yrs. prior to my colectomy in 2004. i am in litigation to prove that acyclovir erroded the mucosa lining of my colon. and as a result triggered uc or viral gastroenteritis. requiring my full colectomy. if you have genital herpes and took acyclovir capsules for it and developed uc or any other digestive problems, please respond to this thread.