The filters in your kidneys are supposed to stop protein from being lost from your blood. Protein loss indicates that you may have some damage to the filters. Usually a 24hr protein collection is done to see how much protein you are losing in a 24hr period. Normal loss is around 150 mg . If your protein loss exceeds 1500 mg a day you would normally be referred to a nephrollogist. from 1500 to 3000 the referral becomes more urgent. Over 3000mg and you are considered to have nephrotic syndrome . Usually in cases where protein loss exceeds 2500 mg nephrollogists may ask you to have a kidney biopsy to try to determine the exact cause. Hope this helps,Ron.