redbuzzard75
02-23-2009, 07:45 PM
I know that oxycontin contains oxycodone. Oxycontin is time released oxycodone. Can anyone tell me how the dose amount works. Like for example: does a 20 mg oxycontin have 20 mg of oxycodone in it? So if this were true a 20 mg oxycontin releases 20mg's of oxycodone over a long period of time. try to say that 3 times fast:dizzy:
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brianpain33
02-23-2009, 07:58 PM
Yes you are correct and I know that Executor knows the exact precise release on the Oxycontin. I think that half of it is released after an hour and then the other half released after 8 hours but don't quote me on that. I do know that most people do not get 12 hours of relief and are taking it 3x/day instead of 2x/day.
brian
brian
redbuzzard75
02-23-2009, 08:02 PM
yeah I take it 3 times a day so 8 hours makes sense. Thanks for the quick reply
KM79
03-01-2009, 01:49 PM
oxycontin for me was awful! I was taking 10mg x 2 a day and after 2 weeks i didn't know who i was... really messed with me. Also, because it wasn't working fast enough or frequently as stated, i was taking more ofen then i should and in the mind state, i was very frustrated, in pain and confused. I take the fast release oxycodone which works great for me and now am trying the norspan patch. Good luck with the slow release and i hope it works for you better then me xx
Executor
03-01-2009, 11:31 PM
The exact release mechanism is a trade secret...You cannot find the information anywhere. I've heard some say that half is released upon taking the med and the other half is released approximately six hours later. So, for a 20mg, 10mg would be released immediately, and then the other 10mg six hours later. However, my PM Doc told me that 10% is released immediately and then the 90% released proportionally over next 10 hours.
Regardless of the forumla, it is designed to release the Oxycodone over time via the time release mechanism in the pill. This is what makes the med long acting. If you read the prescribing white paper from the manufacturer, it will tell you that for any given dose of OC, the blood plasma level (BPL) is higher on OC than the same amt taken of Oxycodone instant release over the same period.
For example, OC 10mg taken every 12 hours results in a higher BPL than if you take 5mg of Oxycodone every 6 hours. Not only does the BPL get higher, but is sustained. This is why the med is so effective for many.
Brian is correct in that most patients report that the med does not last 12 hours. 3 x per day, or every 8 hours, has become pretty standard by many.
Hope this answers your questions.
Regards,
Ex
Regardless of the forumla, it is designed to release the Oxycodone over time via the time release mechanism in the pill. This is what makes the med long acting. If you read the prescribing white paper from the manufacturer, it will tell you that for any given dose of OC, the blood plasma level (BPL) is higher on OC than the same amt taken of Oxycodone instant release over the same period.
For example, OC 10mg taken every 12 hours results in a higher BPL than if you take 5mg of Oxycodone every 6 hours. Not only does the BPL get higher, but is sustained. This is why the med is so effective for many.
Brian is correct in that most patients report that the med does not last 12 hours. 3 x per day, or every 8 hours, has become pretty standard by many.
Hope this answers your questions.
Regards,
Ex
lisam1120
03-02-2009, 01:57 AM
Brian,
I've never understood how the slow release meds work, and I gave up trying to figure them out awhile ago, but I know they do. However i'm already having a problem with the hours it lasts. I take 80mg OC 3 times a day, and then i'm allotted to take 30mg IR 3 x a day for BT pain. I am finding that the 80mg is only lasting approx 6 hours even with BT rescue meds and they dont last but maybe 2-3 hours for me. I have very fast metabolism and burn through meds very quickly and I sooooo wish that I had a slow metab rate because I know that if I did, then I wouldnt build up a tolerance so quickly to them and the meds would last much longer.
Having a fast metabolism rate makes it very difficult to explain to the doctor that after 2 months of being on a med, that i'm already tolerant to it. I thought that I would have better luck with the LA med, but thats just not happening.
Either way, I'm still happy with the relief that I do get from the LA and SA combined, its certainely much better than taking 16 30mg oxycodones a day and YES that is what I was prescribed to take by my Rhuemy prior to seeing a PM doc. There are days though, I will suffer through some pain, but I just bite the bullet and cope with it. I would rather go through a few days of pain, than to have to explain to my doc that the meds are not keeping me at the level we were so happy with everyday in the begining.
Hope your doing well and can get your pain under control.
Lisa
I've never understood how the slow release meds work, and I gave up trying to figure them out awhile ago, but I know they do. However i'm already having a problem with the hours it lasts. I take 80mg OC 3 times a day, and then i'm allotted to take 30mg IR 3 x a day for BT pain. I am finding that the 80mg is only lasting approx 6 hours even with BT rescue meds and they dont last but maybe 2-3 hours for me. I have very fast metabolism and burn through meds very quickly and I sooooo wish that I had a slow metab rate because I know that if I did, then I wouldnt build up a tolerance so quickly to them and the meds would last much longer.
Having a fast metabolism rate makes it very difficult to explain to the doctor that after 2 months of being on a med, that i'm already tolerant to it. I thought that I would have better luck with the LA med, but thats just not happening.
Either way, I'm still happy with the relief that I do get from the LA and SA combined, its certainely much better than taking 16 30mg oxycodones a day and YES that is what I was prescribed to take by my Rhuemy prior to seeing a PM doc. There are days though, I will suffer through some pain, but I just bite the bullet and cope with it. I would rather go through a few days of pain, than to have to explain to my doc that the meds are not keeping me at the level we were so happy with everyday in the begining.
Hope your doing well and can get your pain under control.
Lisa