Hi. I am scared to death and I hope you folks can help me. I have thyroid disease so I am taking thyroid medication which can deplete your bones of calcium at high doses. I also have arthritis. I wanted to get pregnant so I went off of my anti-inflammatory drugs. I got a bad flare up of pain so I started a prednisone taper starting at 30 mg per day and decreasing the dose by 5 mg every 4 days. I was on these two medications for 9 days before I started feeling badly. I went off the thyroid meds completely but am continuing to finish my course of prednisone. Now I have had a sore back(feel it in the bones, not the muscles) for the past 6 days. It is not like a normal back ache for me. It hurts mid and lower back and the normal things like heat and activity don't seem to help. I have since found out that prednisone enhances my thyroid medication making it more powerful.I am worried that in that short of a time frame I may have given myself osteoporosis. Does anyone know if this is possible? I am so scared and feel so stupid that I don't want to tell my doctor what I did. All of the information I can find on osteoporosis says that there aren't really any symptoms until you get your first fracture. I have quite a bit of pain. Can somebody tell me what their first signs were?