Wes1212
07-17-2003, 04:59 PM
hey matt, did you start the pegasys yet?
Sponsor
grizzk62
07-17-2003, 11:28 PM
Hey Wes,
Yes I did start about 3 weeks ago. Terrible side effects at first. Its getting better. I still have to take marinol and all. I don't have to take dilaudid anymore for BT pain still useing Oxy IR 20mgs upto 4times a day. Still at 70 mgs methadone. Oh well. At least the sides aren't getting worse only better. I just took my 4th shot week 4 now. And I'm starting to feel tired and sick need to go thanks for asking...
Matt
Yes I did start about 3 weeks ago. Terrible side effects at first. Its getting better. I still have to take marinol and all. I don't have to take dilaudid anymore for BT pain still useing Oxy IR 20mgs upto 4times a day. Still at 70 mgs methadone. Oh well. At least the sides aren't getting worse only better. I just took my 4th shot week 4 now. And I'm starting to feel tired and sick need to go thanks for asking...
Matt
Wes1212
07-18-2003, 12:20 AM
matt, does roche have a nurse hotline for pegasys patients to call about side effects?
i hope it gets easier every week until you're done!
[This message has been edited by Wes1212 (edited 07-17-2003).]
i hope it gets easier every week until you're done!
[This message has been edited by Wes1212 (edited 07-17-2003).]
Autumn Angel
07-18-2003, 07:29 PM
Dear Matt...I hope you are feeling better soon. Been watching my parents house while they are away. I pop home when I can. Hope to catch up with you soon my love and prayers are with you as always.
Luv
Autumn.
Luv
Autumn.
grizzk62
07-18-2003, 09:30 PM
Hey Autumn,
Hey ole pal ole friend of mine. today is beter. I took my 4th shot thursday night so for the most part I'm over the side effects. Back to reg meds. I think about you everyday and keep missing you online so that we can chat and catch up. I miss you and love ya tons. My deppression is alot better. Doc raised my wellbuttrin from 150mg a day to 300mgs a day. And he also switched me to focalin. instead of adderall. It is sposed to be like a refined form of ritalin. Only better than ritalin and it has helped tremendously. My pain level is better. Still just using the Oxy IR for BT pain. I still have a bunch of dilaudid if it gets worse.
enough about me how are you doing and all. Hows your daughter dealin w/the break up. Let her know that I'm pulling for her. Chars says hi as well. Hows your pain level doing. have considered going back on the long acting meds. Maybe we need to talk about it some more. Anyhow I do miss ya and love ya.
And WES thanks for your concern. Its nice knowing that there is someone on this board that knows exactly what I'm going thru. I hope all is well w/you. If I can help at all please let me know.
Take care all.......
Matt
Hey ole pal ole friend of mine. today is beter. I took my 4th shot thursday night so for the most part I'm over the side effects. Back to reg meds. I think about you everyday and keep missing you online so that we can chat and catch up. I miss you and love ya tons. My deppression is alot better. Doc raised my wellbuttrin from 150mg a day to 300mgs a day. And he also switched me to focalin. instead of adderall. It is sposed to be like a refined form of ritalin. Only better than ritalin and it has helped tremendously. My pain level is better. Still just using the Oxy IR for BT pain. I still have a bunch of dilaudid if it gets worse.
enough about me how are you doing and all. Hows your daughter dealin w/the break up. Let her know that I'm pulling for her. Chars says hi as well. Hows your pain level doing. have considered going back on the long acting meds. Maybe we need to talk about it some more. Anyhow I do miss ya and love ya.
And WES thanks for your concern. Its nice knowing that there is someone on this board that knows exactly what I'm going thru. I hope all is well w/you. If I can help at all please let me know.
Take care all.......
Matt
Autumn Angel
07-18-2003, 09:52 PM
Dear Matt :) I miss you alot. I am glad you are feelin better. That depression had me worried because I felt so helpless and couldnt do a thing to make you feel better :( I am glad your pain level is better and mine well its doin ok. I am down from 8 percs a day ( 2 ...4 times a day) to 6 a day. And going to try and keep level and possibly fix things. We can talk more about that soon. Say hi to Char for me ok? I will catch up with you soon my friend :) Love ya Bunches ;)
Always
Autumn.
Always
Autumn.
Wes1212
07-27-2003, 04:36 AM
Matt, I hope you have the energy to read this, maybe your doc needs to see it.
Acta Anaesthesiol Scand. 2003 Aug;47(7):794-803. Related Articles, Links
What anaesthetists need to know about viral hepatitis.
Lentschener C, Ozier Y.
Department of Anaesthesia and Intensive Care, University Paris V - Rene Descartes, Hopital Cochin, Assistance Publique - Hopitaux de Paris, Paris, France.
BACKGROUND: Viral hepatitis is a major world-wide public health issue. An increasing number of virus hepatitis carriers with acute or chronic hepatitis at all stages of the disease will be referred to anaesthetists. An update of what anaesthetists should know about viral hepatitis was believed to be warranted. METHODS: The present review focuses on (a) diagnosis criteria and main biological and clinical patterns of acute and chronic hepatitis, and (b) extrahepatic manifestations, and adverse effects resulting from specific drug therapy likely to influence anaesthetic care. RESULTS: Elective surgery should be postponed and any medications that could be harmful to the liver should be disregarded in patients suspected of having acute viral hepatitis. A prothrombin time decrease to less than 50% (INR > 1.75) is the first sign of acute severe liver failure. Extrahepatic manifestations resulting mainly from small- and medium-sized vessel alteration, and adverse effects caused by specific drug therapy are associated with chronic viral hepatitis and are likely to alter anaesthetic care. A titrated anaesthesia should be provided and agents not eliminated by the liver should be favoured. Vasopressor therapy should be administered early to control a systemic intraoperative blood pressure decrease associated with a high cardiac output. Prophylactic antibiotics should take into consideration the risk of translocation of gut bacteria to the systemic circulation. Prophylactic guidelines of hepatitis nosocomial transmission should be respected. CONCLUSIONS: Anaesthetists are likely to play a key role in immediate acute hepatitis and chronic hepatitis perioperative assessment and care."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12859298&dopt=Abstract
[This message has been edited by Wes1212 (edited 07-27-2003).]
Acta Anaesthesiol Scand. 2003 Aug;47(7):794-803. Related Articles, Links
What anaesthetists need to know about viral hepatitis.
Lentschener C, Ozier Y.
Department of Anaesthesia and Intensive Care, University Paris V - Rene Descartes, Hopital Cochin, Assistance Publique - Hopitaux de Paris, Paris, France.
BACKGROUND: Viral hepatitis is a major world-wide public health issue. An increasing number of virus hepatitis carriers with acute or chronic hepatitis at all stages of the disease will be referred to anaesthetists. An update of what anaesthetists should know about viral hepatitis was believed to be warranted. METHODS: The present review focuses on (a) diagnosis criteria and main biological and clinical patterns of acute and chronic hepatitis, and (b) extrahepatic manifestations, and adverse effects resulting from specific drug therapy likely to influence anaesthetic care. RESULTS: Elective surgery should be postponed and any medications that could be harmful to the liver should be disregarded in patients suspected of having acute viral hepatitis. A prothrombin time decrease to less than 50% (INR > 1.75) is the first sign of acute severe liver failure. Extrahepatic manifestations resulting mainly from small- and medium-sized vessel alteration, and adverse effects caused by specific drug therapy are associated with chronic viral hepatitis and are likely to alter anaesthetic care. A titrated anaesthesia should be provided and agents not eliminated by the liver should be favoured. Vasopressor therapy should be administered early to control a systemic intraoperative blood pressure decrease associated with a high cardiac output. Prophylactic antibiotics should take into consideration the risk of translocation of gut bacteria to the systemic circulation. Prophylactic guidelines of hepatitis nosocomial transmission should be respected. CONCLUSIONS: Anaesthetists are likely to play a key role in immediate acute hepatitis and chronic hepatitis perioperative assessment and care."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12859298&dopt=Abstract
[This message has been edited by Wes1212 (edited 07-27-2003).]
Wes1212
07-27-2003, 04:42 AM
Matt, Heres another:
Hepatogastroenterology. 2003 Jul-Aug;50(52):1149-54.
HCV infection and extrahepatic manifestations.
Nocente R, Ceccanti M, Bertazzoni G, Cammarota G, Silveri NG, Gasbarrini G.
Emergency Department, Rome University, La Sapienza, Italy. rnocente@libero.it
Hepatitis C virus infection is associated with various extrahepatic manifestations such as mixed cryoglobulinemia, membranoproliferative glomerulonephritis and porphyria cutanea tarda. The link between mixed cryoglobulinemia and hepatitis C virus infection is actually well known. Interferon alpha therapy decreases hepatitis C viremia and improves the clinical signs and biochemical abnormalities of cryoglobulinemia. The rare combination of hepatitis C and panarteritis nodosa has still not been confirmed. The sicca syndrome also seems to be associated with hepatitis C virus, but this is not the typical Sjogren's syndrome. It is not yet well established if hepatitis C virus plays a pathogenic role in the development of thyroid dysfunction and autoimmune thyroiditis. Probably interferon therapy may be implicated in the development in this and other extrahepatic manifestations of hepatitis C virus infection. Although an epidemiological association of hepatitis C with lichen planus, neuropathies and other diseases has been observed, the etiological role and the pathogenic involvement of the hepatitis C infection remains unclear. Extrahepatic clinical manifestations are frequently observed in hepatitis C virus patients and involve primarily the joints, muscles, and skin. The most frequent immunological abnormalities include mixed cryoglobulins, antinuclear antibodies, and anti-smooth muscle antibodies.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12846002&dopt=Abstract
[This message has been edited by Wes1212 (edited 07-27-2003).]
Hepatogastroenterology. 2003 Jul-Aug;50(52):1149-54.
HCV infection and extrahepatic manifestations.
Nocente R, Ceccanti M, Bertazzoni G, Cammarota G, Silveri NG, Gasbarrini G.
Emergency Department, Rome University, La Sapienza, Italy. rnocente@libero.it
Hepatitis C virus infection is associated with various extrahepatic manifestations such as mixed cryoglobulinemia, membranoproliferative glomerulonephritis and porphyria cutanea tarda. The link between mixed cryoglobulinemia and hepatitis C virus infection is actually well known. Interferon alpha therapy decreases hepatitis C viremia and improves the clinical signs and biochemical abnormalities of cryoglobulinemia. The rare combination of hepatitis C and panarteritis nodosa has still not been confirmed. The sicca syndrome also seems to be associated with hepatitis C virus, but this is not the typical Sjogren's syndrome. It is not yet well established if hepatitis C virus plays a pathogenic role in the development of thyroid dysfunction and autoimmune thyroiditis. Probably interferon therapy may be implicated in the development in this and other extrahepatic manifestations of hepatitis C virus infection. Although an epidemiological association of hepatitis C with lichen planus, neuropathies and other diseases has been observed, the etiological role and the pathogenic involvement of the hepatitis C infection remains unclear. Extrahepatic clinical manifestations are frequently observed in hepatitis C virus patients and involve primarily the joints, muscles, and skin. The most frequent immunological abnormalities include mixed cryoglobulins, antinuclear antibodies, and anti-smooth muscle antibodies.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12846002&dopt=Abstract
[This message has been edited by Wes1212 (edited 07-27-2003).]
grizzk62
07-27-2003, 10:38 AM
Wes,
Hey my friend thanks for the reading materail and the site links. I found that to be very interesting and informative. I do see my doc tommorrow at 9:30 and I will bring this along with me and talk with him about this. I still get pretty sick after each shot but it doesn't last as long anymore. Again thanks for passing along the info. How are you doing anyway. Whats your statits and health been. I hope that your doing better. Take good care and I will let you know what my doc says in regard to this info.
Matt
[This message has been edited by grizzk62 (edited 07-27-2003).]
Hey my friend thanks for the reading materail and the site links. I found that to be very interesting and informative. I do see my doc tommorrow at 9:30 and I will bring this along with me and talk with him about this. I still get pretty sick after each shot but it doesn't last as long anymore. Again thanks for passing along the info. How are you doing anyway. Whats your statits and health been. I hope that your doing better. Take good care and I will let you know what my doc says in regard to this info.
Matt
[This message has been edited by grizzk62 (edited 07-27-2003).]
Wes1212
07-27-2003, 11:28 AM
Matt, I relapsed. Found out last week. I'm still trying to keep on keeping on, though! Thanks for asking :)
I hope the shots keep getting easier for you! I know it seems like a long road, but time still has the tendency to move along!
Have you ever looked into Dr. Cecil's technique? I know alot of people don't agree with him but, I know of a few people who were given up on that he has done very well with.
[This message has been edited by Wes1212 (edited 07-27-2003).]
I hope the shots keep getting easier for you! I know it seems like a long road, but time still has the tendency to move along!
Have you ever looked into Dr. Cecil's technique? I know alot of people don't agree with him but, I know of a few people who were given up on that he has done very well with.
[This message has been edited by Wes1212 (edited 07-27-2003).]