I have been abusing Tylenol Cold and Flu Extra Strength pills the last year and a bit. Usually 3-4 times a week, on average, I would consume 3-4 of these pills each day to attain that euphoria and eventual tired feeling. I understand the long-term effects on the liver etc. I don't however have a dependency on these pills as I have the will to not take them for 4 or 5 days often. QUESTION: Will abusing tylenol like I have reduce the effectiveness of any anti-biotic I might take in the future? (eg. Doxycycline, Cipro etc.)