I tried Syn-Flex for 30 days. I originally was on Glucosamine Sulfate 1500 MGS per day for about 2 months when I decided to see what Syn-Flex was like. After 30 days, I felt no different than when I was on the pills so I went back. The pills are alot cheaper by far. So starting off on it and sticking with it might prove effective, but in my case, I could tell no difference. I know, reading the website, you would think it was great. Some complain about the taste, I didn't think it was so bad, kinda like a green apple. Those are my thoughts. Hope this helps.