Re: UCTD or Seronegative RA?
UCTD is an overlapping condition of several autoimmune disorders, usually lupus, plus signs of RA, Sjogren's (the dry eye-mouth-vagina) problem, dermatomyositis, scleroderma, etc in any combination. These patients usually have positive RNP (high titer) antibodies as well as others. Differentiation of lupus and RA ARTHRITIS is the presence of erosions in the joints. RA causes them, lupus does not. Xrays or MRI clarify that. Also, lupus usually doesn't cause joint deformity, RA does.
There is a new lupus test that is more sensitive than the standard ANA. It is called AVISE-SLE, and I would ask for that if there is any doubt after you see the rheumatologist. You are headed in the right direction, and with clarity of diagnosis and then getting on treatment should feel much better, but nothing works overnight, so be patient as you work through the meds and see how you respond.