Re: HLAB-27+ gene marker=Reactive Arthritis
I have the HLA-B27 antigen and it is highly misunderstood by most doctors.
It is apparently associated with many autoimmune reactions, but most rheumatologists associate it Anklosing Spondylitis. This illness is multi-faceted--it affects joints, but also eyes, gastrointestional system, etc.
I have it and don't have AS, but am trying to figure out why I have a elevated sed, rate, low immuglobulin levels, that are not low enough for me to be a candidate for IGG infusions.
My symptoms keep changing. Go to the Ankylosing Spondylitis Association website. There are many women who have many different types of autoimmune illness, like endometriosis, sogjren's, fibromyalgia---all illnesses that there is little understanding of.
I can't find a doctor who can help me and it is very, very frustrating.
My immunological study shows I have a number of elevated cytokines and another shows I have high vulnerability to infections. TNF's are contraindicated with people who are at risk of high infection. Are our systems turned on by reactions to bacteria? This is not where the drug companies are headed.