I can certainly attest to the power of hormones. My bipolar kicked in when I was 13 - about the time my body started producing hormones.
They put me on the pill at 16 to regulate my periods and I think that was a bit of a help with the bipolar at the time.
I wasn't properly diagnosed and put on rx until I was 30 so you can imagine the disruptions in my live between 16 & then!