I haven't had ANY anxiety problems with seroquel. The weight gain I'm not so sure about. I did gain weight while on seroquel but it could be a coincidence, I did eat nothing but cake, cookies, and pie for a month. Did seroquel make me crave these things and thusly indirectly cause weight gain? Who knows. I won't rule out anything at this point. But if you are strong of will and resistent to cravings, it could be the med for you! I really love seroquel. I've written songs about its glory. I sleep like a rock, I don't cycle, I'm not depressed, I'm not manic. I'm just fat. And that I can live with!