Yes. That has happened to me before. It especially was worse during a major manic episode where I was in psychosis. Til this day, I still am not able to recollect a lot of things, and hubby would rather keep it that way for my safety for fear of me having another episode due to all the stupid things I did to him and our family. I do have flashbacks to that episode, and can remember blocks of things but they don't make sense, though I know the pictures of memory are reality and happened during that time frame, it is just that my memory was very foggy and strained due to stress from being so messed up and not medicated right. Once I was put on the right dosages of meds, within a week or so, I was on my way to 'normalcy' and snapped right out of it though I still had a few issues due to the episode, like insecurity, self-esteem, and severe depression followed etc.
If your husband is in a manic episode, please make it 'your business' to attend his pdoc appointment with him. It a person is married to a Bipolar person, or person with a mental illness, it is their responsibility to look after themselves as well, and their part in the relationship too. That means taking charge of the other spouses issues too. If they are sick, then they basically are not making wise decisions (been there and done that) and need assistance from their significant other to do so for them, plus, he might be telling the pdoc 'I'm just fine', and that would be awful because most people who are manic are in full denial of the situation at hand. I was, and it is very common of that to happen.
You matter in the relationship as well. I said similar things to my DH when I was manic. I never meant to hurt my DH nor say those things because it is just 'not my nature' and because I absolutely love my hubby. It was the illness. And, thank goodness he believed in my love for him through all of that crap I put him through. If you know the level of your relationship, and how much each of you care for each other, then you know he isn't really meaning divorice. It is the illness, and he needs to seek professional help asap with your guidance, so he knows you love him, and that he also loves you.
Hang in there. This is not an easy road to be married to a person with a mental illness. My DH puts up with a lot each day. I'm a challenge to be married to. I'm stabilized but am a rapid cycler- so I will mood swing every now and then due to exterior factors (family issues, stress, etc.). Things are good in my life now. There is so much to be thankful for.
Take care of yourself. Don't forget to do that. Take time for you!