Depakote: Side Efffects update
some weeks ago someone asked about potential side effects of Depakote, well having just had my dose upped from 1000 - 2000mg I can reveal a few.
To be honest most are listed, but interestingly I actually didn't know about them before I actually got the symptoms and then read the literature and I've been on it for 6 years!
I went from 1000 - 1500 about 5 weeks ago. Within 2 weeks my psych put it up again to 2000mg.
My symptoms included, at the first increase, nausea (intense) in the morning and evening; blinding headaches; and no apparent change in the frequency of the cycles. Even with discussing these symptoms my psych decided that I was still too manic and upped it again. The nausea got worse although did seem to be offset as soon as I took the medication unless i changed my routine - like left dinner an hour later or so and then I found that the nausea continued after eating because I'd taken the tablets before food not with it.
I also noticed that i was bruising really easily and so now i'm waiting for blood tests on platelet levels apparently. I also have a low sodium serum level at the moment too.
On the positive side, 2 weeks in to the 2000mg and the nausea and headaches are fading. I feel more eloquent and able to deal with things although my irritability a still a little raw. But things are definitely on the up.
Hope this helps