Seroquel, how long to be effective? - Bipolar Disorder Message Board

tocoja13 · 04-21-2008, 07:38 PM

My doc started me on Seroquel for Depressive phases of Bipolar, I'm at 300mg and have been taking it since 4-10-08. I started with the starter pack and was up to 300mg by the fourth day. When do you feel the significant desired effect? I have serious daytime tiredness and sleepiness but the moods are better, I was hoping for better depression effect. Thanks!

katlin09 · 04-22-2008, 09:57 AM

You're still on a relatively low dosage...you can go up to 800mg for a normal adult dosage according to my pdoc. I just got raised to 450 yesterday, but also taek zoloft, topomax, and started on lamictal. The seroquel has been very helpful for moods and irritation, but the depression seems to get bad each time I get used to a higher dosage. So maybe you need to talk to your pdoc about adding something to help with the depression I guess it just depends on how bad your depression is, maybe you just need a higher dose? Just a thought. I've been taking the Seroquel since the end of December. I have BPII with Severe BP Suicidal Depression.

Llama · 04-22-2008, 10:42 PM

Generally they say to give at least a full month (once at a therapuetic dose of course) to see if a med is working or not.

Kmit is right too. You may need a higher dose or another med added if the seroquel isn't cutting it. I do know that seroquel is approved for bp depression so I hope that it starts working for you soon.

katlin09 · 04-24-2008, 07:20 AM

Toco,

How are you doing on your Seroquel? Has it gotten any better?

janart · 04-24-2008, 02:19 PM

same situation going on here. 300mg couldn't handle the grogginess so started halfing it till doc visit Wednesday. Not doing good as far as depression feelings. What is good to add with it though when you are already too groggy to get out of bed???