Originally Posted by Brandy176
Can anyone explain what rbc and wbc morphology means in a cbc test?
Ok for starters, morphology means science of change. In the RBC (red blood Cells)they start out as reticuloyctes that are manufactured from the bone marrow and a few other places. They then morph in to eyrthrocites ( that which turns the blood red) If the cells are the right size and shape they are thought of as normal. This process takes 120 days from the time they are created to the time that they have done their job, break down and are reabsorbed by the spleen to be cycled and sent back to the bone marrow. If there is any problems such as bone marrow deficiency or malnutrition or disease, then the cells may be smaller or badly shaped oval instead of round. They might be too large or toow small. They may not have enough surface room to transport oxygen like they are supposed to .
The white blood cells are made up of lymphocytes, monocytes, neutophils, eosinophils, and basophils. The sum total of these cells make up your white blood cell count. The neutrophils protect you from fungus and bacterial infections and the lymphocytes have about 3 different types of warriors T-Cells, B-Cells and NK cells. The T- Cells are most talked about in HIV, the B-Cells most often talked about in Lymphomas and the NK cells are the Neutral cells or killer cells that try to protect the other cells from being taken over by disease. They do this by trying to contain or kill the viruses and funguses that routinely attack our bodies on a daily basis that we don't even suspect. Over all the lymphocytes are created and maintain for about 3 days. Then some of them die and others go on to take up residence in our tissues and go from tissue to blood depending on need. There are some of the Lympocytes that are created and last for nearly a life time. Those memory cells have the protection against polio, mumps measles and any other innoculations you may have had as a child or teenager or military person. They also remember things that you got naturally like simple viruses. As we grow older if we have healthy immune systems, we have fewer colds, fewer stomach flus and the like because of our body's memory cells in lymphocytes. When we get cancers, usually our lymphocyte counts go extremely high because the body has detected an invader that seems to act like a virus, but the body starts to create the lymphocytes haphazardly and incompletely which causes a chain reaction of panic in the immune system. Then these poorly made cells die too soon and eventually we have a lymphocyte depletion state. This is what usually finishes people off in hospitals is when their body can not make any more defenses to bacteria and fungus and the rest of the body is too weak to fight as well.