Blood and rheum issues
I have been IgA deficient for at least 20 years. I started getting B12 shots and went off Plaquenil when my red blood cell and hematocrit counts dropped and the RBC size began running up.
After a few months the IgA, HCT and RBCs normalized but IgG Subgroup 1 dropped, my CTD has acted up and RBC size keeps increasing (presently at 108 fl). I now have significant and increasing swelling, pain and redness and in my fingers, hands, feet and ankles, Raynaud's and shoulder weakness. The rheumatologist calls it Sjogren's but I don't have the classic dryness the diagnosis requires or any measurable autoantibodies.
Now the hematologist wants a marrow aspiration and biopsy before they restart the Plaquenil. Can anyone offer any insight, eg, CVID, megaloblastic anemia, undifferentialed CTD, MDS, Sjogren's? Any help would be appreciated.
Last edited by ocelot; 09-07-2009 at 10:53 PM.