Hi, I hate that you have not had any responses. Please know that this is only a laypersons interpretation and you should be able to have your questions answered by your family doctor, rheumatologist , opthamologist or hematologist.
That being said, blood is divided into groups O, A, B, AB and rhesus (rh) factor positive (+) or negative (-). Your wife is blood group B+. The blood CAN also be subdivided further into other blood group systems
. Sometimes this is checked in case a transfusion is necessary?? All individuals carry antigens from other blood group systems and they may develop antibodies if transfused with blood containing antigens absent on their own RBCs. There are many systems.....ie. Lewis, Kell, Duffy, Mcleod, Kidd, Lutheran and P blood group systems to name a few.
The most common phenotype of the P system is P1 and P2. P1 individuals have P and P1 antigens present on the RBC. I believe from reading, but as I said previously I am NOT a professional, that P1 is the most common.
The HLA-B27 antigen is a specific protein exists on the surface of the body’s white blood cells and is associated with ankylosing spondylitis,reactive arthritis, certain eye disorders such as acute anterior uveitis and iritis
, psoriatic arthritis and ulcerative colitis. However, HLA-B27 is found in 5 - 7% of Caucasians who do not have an autoimmune disorder
So P1 has to do with red blood cells and HLA-B27 has to do with white blood cells. I hope that helps a little. Please consult with the opthamologist for more information. Hoppy