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Old 04-05-2009, 12:28 PM   #1
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IBS: Miralax vs Amitiza

Hello,

I have sever Diverticulosis with scarring on both the ascending and descending colon. I've been managing, or trying to manage, the constipation for about three years. The treatment has been Miralax (17 gm) a day and a stool softener. I have been bloated since the first day. Taking less helped the bloating but did not help the painful constipation.

I have recently been diagnosed with IBS as well. I have now been prescribed Amitiza (8mcg) twice a day.

Has anyone used Amitiza as an ongoing treatment option? If it has proved beneficial, have there side effects such as bloating?

Long post for such a brief question; sorry. But, I thank you for any comments. Dejahere

 
Old 04-05-2009, 02:34 PM   #2
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Re: IBS: Miralax vs Amitiza

Hi, I've never used amitiza but I use miralax daily plus fiber. I don't get bloated from the miralax but I take my dose just before bedtime. I got bloated for a while from the fiber but when my system adjusted things were better. Are you eating a lot of fiber in a day? I also have IBS, scarring from hemorrhoid surgery, I just had surgery on an anal fissure in oct. and I don't think things will ever truly be the same. I honestly feel your pain. Finding a balance is tricky. I hope your new meds help you and you start to feel normal again. Suzy

 
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Old 04-08-2009, 02:07 AM   #3
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Re: IBS: Miralax vs Amitiza

Suzy, Thank you for sharing your irritating experience! I do not believe, in all these years, anyone has related having a similar problem with their health. Just knowing I am not the only one who deals with an ailment that interrupts so many work related, social, family, and other commitments. I find it hard to explain why I'm backing out or canceling plans.
I've been trying since 2006 to feel normal. I guess that is not a realistic goal. But, it sounds like your adapting and re-adapting to give yourself longer periods of balance. That is a goal I think I can achieve and be happy with. Your reply really has helped put this thing into a perspective that allows me to maintain a bit of control. Thank you again!
It will be awhile before I know if the new medicine will reduce the constant bloat and discomfort. So far, it seems to be working. However, after the first five days, I started experiencing that terrible cramping that had once led to bathroom "sit ins". Those days were before the Hysterectomy which preceded the "Constipation Blues" that led to the Colonoscopy and the Diverticulosis Diagnosis which soon revealed the bowels were seriously irritable over the whole experience.
The Dr. prescribed some type of anti cramping agent to take when needed, and it worked. So.....bless you. I hear this is one of the most common problems regarding Gastrointestinal ailments. It's nice to meet at least one individual, other than myself, assigned to this Gastrointestinal Sub Category. In truth, I hope they find a cure and we both move out. Until then, stay well and remember you truly helped. My Best, Deja

 
Old 04-19-2009, 08:45 AM   #4
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Re: IBS: Miralax vs Amitiza

HI dejahere,
I was just put on the amitizia about 3 weeks ago. I find that it does soften the stool somewhat, but does not stop my chronic constipation. I"m still having a difficult time evacuating it all upon one sitting. It's more like 8 times a day a little at a time, but softer.
I AM finding that the "amitizia" is causing stomach pain and stomach upset. as if I ate something bad feeling. like you just feel out of sorts and yucky.
I'm trying to stick it out and see if my body eventually gets used to it thinking maybe this side effect will subside, but so far, it's not.

Don't be afraid to try it. Just because I have this side effect from it doesn't mean you will. PLUS it does not cause any bloating to my stomach and no weight gain. As a matter of fact, I've dropped a lot of weight in such a short amount of time without even trying. I had no appetite recently or very little when I did.
I hope one of them work for you.

Linda

 
Old 04-20-2009, 12:26 AM   #5
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Re: IBS: Miralax vs Amitiza

Hi Linda,

Thank you so much for sharing your experience. I really hope things have balanced out.

I recall taking Amitiza briefly just over a year ago. I took it wrong. I mean, rather than one twice a day I'd take two at one time. I know exactly what you mean by "yucky" feeling. I felt weak and nauseous.

I also feel it does not help with the evacuation. The stool is not soft. At first, I thought it was going to lead me back to a normal state. That was just the constipation...or hard stools returning. The Dr. still had Miralax prescribed. But, the one huge benefit was the same as yours; no more bloating! That sick feeling has gone with the lower dose at one twice a day. What I did was add a stool softener. It helps, but not enough all the time. So when I get too uncomfortable I add a dose of Miralax.

I still carry water weight but feel using the Amitiza might help me lose some of the twenty pounds I've gained. You've given me hope.

Drop in again and let me know how your fairing. Thank you so much, Leslie

 
Old 04-23-2009, 08:55 AM   #6
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Re: IBS: Miralax vs Amitiza

Leslie,
thank you for your reply and the suggestion as well.

I'm not going to take the mirilax, but I do need to perform another cleansing since last week when I was forced to use the mirilax for the colon prep.
I've been blocked ever since.
I am getting so discouraged and unhappy with this problem. I know certain foods aggrivate my condition as well and will only bind me up further. so I have to stay away from those particular culprits.
meanwhile, today I'm going to take my 1 teaspoon of sodium bicarbonate and mix it in 6 oz of water and keep my fingers crossed that it performs a total cleansing so I can be comfortable again.
I'm telling you. JUST when I think my intestines are back to normal, something winds up ruining it.
I consumed way too much sodium the past two days by eating the wrong foods. I had two slices of pepperoni pizza last night which is so high in sodium plus cereal which must have a very high sodium content because when I woke up this morning, my knuckles that have this new arthritis in them were swollen twice the size they normally are and my fingers like breakfast sausages and my eye lids heavy with fluid in them. I felt so horrible in all my joints, including my hip joints.
so things are starting to build up for the worst.
I wish I could get back to being normal, or close to it anyway.
I thank you for your support and it feels good to be able to come to the board and just let it all out.
I just don't want to sound like i"m a constant complainer.

let me know how you're making out.

Linda

 
Old 12-05-2009, 12:49 AM   #7
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Re: IBS: Miralax vs Amitiza

Quote:
Originally Posted by NY 1009 View Post
Leslie,
thank you for your reply and the suggestion as well.

I'm not going to take the miralax, but I do need to perform another cleansing since last week when I was forced to use the miralax for the colon prep.
I've been blocked ever since.
I am getting so discouraged and unhappy with this problem. I know certain foods aggravate my condition as well and will only bind me up further. so I have to stay away from those particular culprits.
meanwhile, today I'm going to take my 1 teaspoon of sodium bicarbonate and mix it in 6 oz of water and keep my fingers crossed that it performs a total cleansing so I can be comfortable again.
I'm telling you. JUST when I think my intestines are back to normal, something winds up ruining it.
I consumed way too much sodium the past two days by eating the wrong foods. I had two slices of pepperoni pizza last night which is so high in sodium plus cereal which must have a very high sodium content because when I woke up this morning, my knuckles that have this new arthritis in them were swollen twice the size they normally are and my fingers like breakfast sausages and my eye lids heavy with fluid in them. I felt so horrible in all my joints, including my hip joints.
so things are starting to build up for the worst.
I wish I could get back to being normal, or close to it anyway.
I thank you for your support and it feels good to be able to come to the board and just let it all out.
I just don't want to sound like i"m a constant complainer.

let me know how you're making out.

Linda
Hi Linda! I had lost the link to this site some time ago and came upon it by accident. I am glad I did. But, unfortunately I have not experienced any improvement. Trying to find answers in the medical community left me feeling I was viewed as a 54 Yr. old Hypochondriac. I have developed other health related issues during this same period; likely related.

Every visit since I started trying to really get help last spring, I have dumped every new and old symptom on the Dr's, head. I feel if I just say the right word it will get him to think deeper. I keep thinking he will jump up, announce he's figured it out, and I will be better again. I will live my life outside my intestinal track, food pantry "with practically nothing that I can tolerate" foods.

It came to the point where I just gave up. He will only focus on one thing...My neck. I believe it was due to the fact he could easily refer me to a specialist. The diverticulitis and total inability to empty my bowel, seem to have been forgotten. It is scary when I fill up so badly I find it extremely difficult and painful to go from a lying down position to sitting. It feels as if a cinder block is in there.

The only thing I learned, that might help: The doctor who originally diagnosed the scared walls on both sides of my colon did take some X-Rays that showed the bowel was moving through the intestine with Miralax and the stool softeners. I was told I likely had a rectocele (The bottom wall of the vagina weakens with age or after delivery a large baby first go around) and stretches when the rectum fills up.. The rectum fills and is given plenty of room to save the bowel as the vaginal wall stretches to acommodate. This makes it impossible for the rectum to function normally.

He wanted me to see another GI specialist to be sure no additional surgery was necessary. He did not want to have his work undone and have to redo. The rectocele can be fixed.

That is my next step. Everything I've read...and applying it to what I feel physically...points to that. I'm not sure I am spelling it right...but I believe it is Rectocele.

I've experienced everything you mentioned...swelling and all. One day I'm wearing a pair of jeans, the next they are seriously too small, three days of torture, one good day and they fit, and then it all starts over. I will book mark this page. And, hopefully you will read this. I will keep you posted.

I'd love to know how things are going for you!

DH

 
Old 12-05-2009, 05:50 AM   #8
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Re: IBS: Miralax vs Amitiza

HI DH,
It's so good to hear back from you after all this time.
I too haven't been on the boards like I used to be,but
am back now and glad to see I had a reply from you. I'm glad to see
they found out you have the rectocele. I'm not glad you have it, but at least they have found this and can fix it.

I started taking the Amitiza on a daily basis figuring I'd
give it a try again because I started getting
the same deep cramping pain around the appendix area.
My family dr. said I might have either scar tissue or possibly a hernia and wanted me to see my gastro dr. to see what he wants to do about it.
the only thing is, MY doctor was all booked up and I'd have to wait weeks to get in, so I took his associate whom I never used before and he refused to perform exploratory surgery fearful it would cause more adhesions.
so he told me to take the amitzia 2x's a day after a meal.
I only take one a day and that seems to work for the most part. but I still am having bouts of blockage.
I wound up in the emergency room again two weeks ago.
I went out for lunch with my brother, got home, had some icecream,
took a nap and was awakened by this yucky uncomfortable feeling
in my abdomen,
It eventually became worst over the hours and I tried so hard
to stick it out and had my fiance' go to the pharmacy and
pick up some gas relief medicine thinking this was the culprit.
it didn't work.
the pain started at 3pm and I wound up going to the ER at 9pm
I didn't get released till 3pm and on my way back from the
hospital my car broke down on the dark, back roads that led
to our home. I was so exhausted!

After a Cat Scan with no contrast, an xray and blood work, the new dr. that came on 2nd shift told me that things showed up on the cat scan but not on the blood work, also stating he didn't see me when I first came in so didn't get the whole picture of my situation and basically said there's nothing wrong and sent me home. can you believe this?
talking about feeling like a hypochondriac?
I was soooo embarrassed.
but he did tell me I needed to follow up with a gastro dr, and I dont' see him till next week.
meanwhile, the CT scan showed increased stool,questionable thickening of the small bowel LUQ suggesting an infectious or inflammatory enteritis, minimal fluid fluid adjacent in to the inferior tip of right hepatic lobe. indicates an acute process whose epicenter is unclear.
what on earth is an "epicenter anyway?
consider hepatitis or other liver pathology (which is somewhat limited in evaluation since no IV contrast was given), occult bowel pathology or even pelvic inflammatory disease although no pelvic abnormalities are seen other than trace pelvic free fluid and patient MAY BE s/p (status post) PARTIAL hysterectomy.
these are the radiologists words, not mine.
They fax over the results of the ct scan to a doctor who works over night some where, not in the hospital, because the 2 radiologist doctors on staff normally are only in the hospital during day hours. the tech told me the other doctor will read the report and then write up a 2nd report.
I never got to see the 2nd report and am going by the 1st one only.

How would you interpret the results on this report after going into the hospital with acute abdominal pain that's happened before in my past and was told at the last episode over the phone from my gastro dr that I have IBS. Only because they couldn't find out what is going on.

It simply blows my mind that a radiologist sees this in my abdomen, yet because the blood work is normal, the ER dr. is saying they didn't see anything???
I am SO confused over this mystery acute pain I get on and off through out the past years. I have to make sure when I move that I have a hospital that's close by for times when I get these acute espisodes. now what kind of living is this?

Oh, and one more thing DH, this is the 2nd time a radiologist, a separate radiologist, has told me on a CT report that I am only partial hysterectomy. I even called my gyno's office to ask them to read me my surgical report from 2005 stating that I absolutely have had a total hysterectomy.
how absurd.
I know what I had. but they keep saying it's only partial which leads me wonder what on earth do they keep seeing inside?
I have to wait to see my gastro dr. so I can ask him this question. what do they keep seeing to imply this?

so things aren't going so well for me in the gastro department as I would like them to be. I am anxious to get this doctors visit over with to see what he's going to say.

I am so happy to see you found the healthboards again and glad you bookmarked it. now you can't lose us again.
I wish you the best and hope you have healthy and happy Holidays.

 
Old 06-08-2011, 08:20 AM   #9
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Re: IBS: Miralax vs Amitiza

I was doing Miralax and Fiber.. But since I have a totuous colon air/gas gets trapped which causes me extreme stomach cramping. Because of this I am only able to eat so much Fiber or I am sick in pain. On Miralax its been hard to figure out the perfect dose.. I dont have a BM for 1-2 weeks at a time. So what happens is when I finally do go.. All that Miralax softer stool is there but then I can't stop going to the bathroom. I get so bloated waiting to go that I dont fit in my clothes and look pregnant.

My dr recently put me on Amitiza 24 to try.. 2x a day. Its been3 weeks and still my BM takes a week to happen and then its so soft I cant stop going and then I get diarrhea. I would be fine with this cause its bettet then the constipation and hard painful stools... But the side effects of the medication have been aweful. I have evwn missed work because of them. I always eat with the amitiza as directed to avoid nausea... But Before and after I have a BM I get sick to my stomach... On top of it I feel like I have the flu...aches/pains all over, chills, hot flashes,headache etc. All has come and gone since I started taking it 3 weeks ago. So I know its side effects. At first I told myself deal with it to see if it goes away and to see if the meds work.. But after missing 2 days of work cause I felt that aweful, I stopped taking it. Then one thing I did find beneficial was that some of my bloating went down.

I talked to my GI dr's nurse and she said since bloating was the only side effect from the Miralax that I can choose to stop the amitiza and continue with the Miralax adjusted it until I can
figure out a good dosage. She has a call into my dr to see what I should do next.

For me the bloating sucks so bad.. But its better the having the flu on again and off again.

Any suggestions on bloating and god aweful gas pains/cramping???

The only thing I have now is Gas X, Heathers Tummy Tammers and Fennel tea

 
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