Yes, I've been taking one or more kinds since I was 16 (I am 32 now). Depression and anxiety run in my family. I will take them as long as I need to. I have tried being off of them and switching around meds and doses but I've learned there is no magical pill and as long as I'm functional and feel somewhat normal and happy that that is all I can ask for. Exercising is a huge help as well as eating right. Medication doesn't work alone. It's a lifestyle change.