Sharp headaches are a well-known side effect of caffeine withdrawal. I'm a pretty high-dosage coffee user, and I find that drinking loads of water helps the headaches.
To my knowledge, the effects of MDMA on serotonergic cells is not reversible. The drug kills the cells, and they are not replaced. However, in an unpublished study that I have heard about, the effects of ecstacy seem to correlate with the maximum single dose of the drug (i.e. if you take two pills in a night, the effect is worse than taking two pills a week apart).
As you now realise, ecstacy is bad, m'kay?
C.
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