Topamax & Vision Disturbances - Brain & Nervous System Disorders Message Board

MustangFilly · 02-05-2005, 10:33 PM

I have been taking small doses (75 to 100 mg) of Topamax nightly to help with muscle spasms associated both with MS and Chiari Malformation. This drug is primarily used for Epilepsy, but has been very effective in my case.

However, for about 8 hours after each dose, I experience strange vision disturbances - not quite double vision, more like everything I look at has multiple blurred edges... almost a mirage type quality. I was checked for Glaucoma, which can be a side-effect of this drug, and found to be fine. No other explanation was offered.

Since I only take the medication at bed time, it doesn't really effect me that much, but I am up several times a night, so I do notice it, and it is certainly disconcerting. Has anyone else experienced similar side effects with this medication? Is it serious?

Thank-you!
MustangFilly

FUNKYHEADGIRL · 02-06-2005, 07:56 AM

Hi! I was prescribed Topamax also but I have not decided whether to take it or not based on some undesirable possible side effects. I do remember though that my Dr said if I had any vision issues to contact her immediately.
I'd call your Dr, explain the symptoms and add that you had the glaucoma test too.
On another note, I have Chiari 1 Malformation too! What kind of problems have you had from yours? Has surgery been suggested? I have a world full of back problems and wonder if this could be the "root of all evil" since it is pushing on my spinal cord. Mine was just found about 2 months ago and all my Dr said was I need another brain MRI "to check it" in another month or so.

MustangFilly · 02-06-2005, 09:24 AM

Thanks FUNKY. My doc knows about the vision things, just doesn't know why they are happening. They are definately related to the Topamax, because if I skip a dose, it doesn't happen that night.... Can I ask why the Topamax was prescribed for you?

As for the Chiari, I had the decompression 5 years ago, and it was a life-saver - really. I was in a wheelchair at that point, unable to work or pretty much do anything. I suffered from severe headaches, dizzy spells, muscle spasms, neck pain, black outs, weakness, fatigue.... on and on the symptoms went.

I still have problems, some from the Chiari and some from the MS, and I take a lot of medications to control them, but I have my life back, and at least the problems ARE controllable now. I am no longer in a wheelchair, I work, I am raising my children (single mother) I ride, train and compete with my horses.

I can't say if your back problems are related to your Chiari or not, but if I were you, I would sure try to find out. The condition causes such a wide array of problems, often different in each person, depending on which parts of the brain it is causing pressure in, or whether there is a syrnx involved....

I wish you luck! And if I can help or answer any questions, please fire away.
MustangFilly

stalo · 03-16-2005, 03:45 AM

I took Topamax for over 2 years for headaches with increases in dosage over time however my only side effects were weight loss and slurred speech with occasional clumsiness or stumbling. Last summer I went to bed one night with a bloodshot left eye and remembered that was a side effect listed on the insert given by the pharmacy. The next day I went to the eye dr but was very light sensitive and had a headache/sharp pain in eye and was told I had Iritis. This was a rare side effect but one that could eventually lead to blindness if not addressed. I was put on steroid eye drops to stop the inflammation and told not to take Topamax again as the same result could occur again. Many meds have side effects and I found any changes that occur, I call the pharmacy 1st since they are pretty honest about side effects and more reliable in their info than Dr's are. Since I had a brain tumor removed in 2003 (benign meningioma) I am right on top of my meds and side effects.

heart44 · 03-17-2005, 11:49 PM

Quote:

Originally Posted by MustangFilly

I experience strange vision disturbances - not quite double vision, more like everything I look at has multiple blurred edges... almost a mirage type quality.

Under "Adverse Effects" for topiramate (Topamax):
Vision: vision abnormal (includes vision decreased, vision blurred, visual disturbance, visual impairment, amblyopia); rarely reported: diplopia, glaucoma, myopia, eye pain.

ALSO: 3-17-05 MedlinePlus Newsletter featured an article titled: Topiramate (Topamax) May Impair Cognitive Function. In a study topiramate was compared to gabapentin.

"The risk of impaired cognitive function with topiramate 'appears to be substantial and is at a level that could have significant adverse effects on daily and occupational functioning,' the researchers note."

I'm not a doctor, but it seems that if topiramate is causing impaired cognitive function, this might explain your "strange vision disturbances".

Search for "Topiramate May Impair Cognitive Function" and you should be able to find the article.