Originally Posted by doloresmc
to have had negative PAPs year after year, a negative biopsy, and still end up having some sort of cancer?.
Yes, it is possible. But wait until you have more data to start worrying!
I suggest you go ahead and call your doctor's office to ask if they tested for HPV. I also suggest you ask for copies of your pathology reports from the 2 paps.
If you really want to be certain they check everything, you might ask your doctor about an ECC (endocervical curettage). When he/she does the colposcopy, he/she might take a biopsy of anything that is atypical on the exocervix. The ECC is kind of like a pap, but it scrapes the endocervical canal where the colposcopy can't see.
Think of the cervix like a frosted donut. The colposcopy and its biopsy sample the frosted part. The ECC scrapes the donut hole where the frosting didn't reach. That's over simplification, but the analogy works for me.
Have you scheduled your colpo yet?