Re: Adenocarcinoma in Situ - recurrence after a cone?
I also had recurring AIS after cone biopsy, but not for many years. I had a cone with negative margins, waited 5 yrs (with a lot of monitoring by endocervical curettage - ECC), then had 2 kids before my AGUS came back. Dr recommended hyst then, even though only AGUS was indicated. I had a hyst in Oct and path results came back AIS again. I'm told it should be gone for good now, but I'm still dubious! Part of my decision to go with the hyst was the knowledge that AIS is hard to detect. I had a feeling there was more there than just AGUS, but they can't really tell until they've taken it all out. Lucky for me, I'd already had my kids. You could have some tough choices to make. That's the worst part really. The hysterectomy wasn't all that bad at all.
The difference between CIN3 and AIS is in the origin of the abnormal cells. I'm not sure how they would be able to say you had AIS and then say it was just CIN3. What was the procedure that initially diagnosed you with AIS? ECC? As long as the cone was taken high enough up into your cervix, the cone results would probably be more accurate than the ECC or colposcopy (I read that colpo is not effective at detecting AGUS or AIS). I guess with your results I might be worried that the cone missed the AIS entirely and only detected abnormal squamous epithelial cells. But I'm no doctor. Definitely something to ask about! Thinking of you, and hoping its not serious!