It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....



Cancer: Prostate Message Board
Post New Thread   Closed Thread
LinkBack Thread Tools
Old 07-21-2008, 02:20 PM   #1
Junior Member
(male)
 
Join Date: Mar 2008
Location: palos hills ill usa
Posts: 44
csyleen HB User
Hss anyone had constant elevated PSA levels that wasn't cancer?

Has anyone had elevated PSA levels for a long period of time with no signs of cancer? I am 50 years old and my PSA was 1.9 in 2005. Now it is 4.5 and has remained like at this level since January 2007. I've had a biopsy but I read that a biopsy may miss the cancerous cells. Doc says prostate feels normal. Do I keep getting biopsies? Are all these biopsies harmful? If there is cancer in the prostate can to many biopsies leak cancerous cells to other parts of the body?

 
Old 07-21-2008, 02:29 PM   #2
Newbie
(male)
 
Join Date: Jul 2008
Location: South Carolina USA
Posts: 9
rock51 HB User
Re: Hss anyone had constant elevated PSA levels that wasn't cancer?

Hello, that is what it sounds like to me, they just keep doing biopsys until they find cancer. I just joined the site last week and Jim and daff are very hepful, I go for my first biopsy wednesday, my psa has been in the 3.0 to 3.7 range for the last 3 years, started when I was 49, oh well, part of the process, but I have found the more you read the more scared you are to do anytihing. I am sure you will get some good responses from the guys here, and good luck, Rock

 
Sponsors Lightbulb
   
Old 07-21-2008, 03:42 PM   #3
Junior Member
(male)
 
Join Date: Mar 2008
Location: palos hills ill usa
Posts: 44
csyleen HB User
Re: Hss anyone had constant elevated PSA levels that wasn't cancer?

ROCK...a biopsy with a PSA under 4? I wonder if we have the same doctor. It almost seemed as if he couldn't wait to get me to do a biopsy. It was done in his office so he makes the money from it. He told me any guy over 40 and a PSA over 2.5 should have a biopsy. But I've read almost every article I can on the web and most agree that the older we get, the normal PSA levels rise. Also levels between 4 and 10 are slightly elevated. Levels can easily be caused by an infection of slight enlargement over lots of sex prior to the test. So I would think most doctors would do a second test a several weeks later, maybe with antibiotics, to see if the PSA levels have come down before doing a biopsy.

Last edited by csyleen; 07-21-2008 at 03:42 PM.

 
Old 07-21-2008, 05:23 PM   #4
Senior Veteran
(male)
 
Join Date: Jul 2007
Location: North Carolina
Posts: 571
daff HB User
Re: Hss anyone had constant elevated PSA levels that wasn't cancer?

Quote:
Originally Posted by csyleen View Post
..a biopsy with a PSA under 4?
Besides the absolute level, it's often the rate of increase that can signal the
suggestion that a biopsy be taken. At 64, my PSA showed a year over year
increase, from 2.9 to 3.9. I waited three months for another PSA test, and when that came out to 4.2 I got a biopsy. Result was a 3+4=7 Gleason score, with cancer found in just one of 12 cores sampled. So I actually think I was
fortunate that they found it- if I had 10 cores sampled and they didn't hit the area with the cancer, I would have gone away thinking everything was ok (until the next PSA increase signaled a need for yet another biopsy, most likely). That's why I suggest if you're getting a biopsy, get enough cores to try to find something, if it is there, the first time.

 
Old 07-21-2008, 05:31 PM   #5
Junior Member
(male)
 
Join Date: Mar 2008
Location: palos hills ill usa
Posts: 44
csyleen HB User
Re: Hss anyone had constant elevated PSA levels that wasn't cancer?

DAFF what treatment did you decide on?

Last edited by mod_007; 07-23-2008 at 12:44 AM. Reason: Removed unnecessary quote

 
Old 07-21-2008, 05:57 PM   #6
Senior Veteran
(male)
 
Join Date: Jul 2007
Location: North Carolina
Posts: 571
daff HB User
Re: Hss anyone had constant elevated PSA levels that wasn't cancer?

Quote:
Originally Posted by csyleen View Post
DAFF what treatment did you decide on?
I chose proton beam therapy, a very targeted form of radiation that doesn't have a damaging "exit" dose of radiation as some other forms, so there is less damage to healthy tissue and fewer side effects than many of the alternatives.
Many of my posts have discussed this in much more detail. If you want to keep educating yourself, one of the books I'd recommend is by Robert Marckini, called You Can Beat Prostate Cancer.

 
Old 07-22-2008, 08:42 AM   #7
Member
(male)
 
Join Date: Jul 2007
Location: Houston, TX, USA
Posts: 74
Kemahsabe HB User
Re: Hss anyone had constant elevated PSA levels that wasn't cancer?

Sorry to hear from you under these circumstances. I'll give you my PC tale and you can add it to what you've learned. My first PSA 10 years ago (age 51) came in at 4.5. I waited a year for a retest (4.7) and was biopsied (the first of three). Six months later my PSA was 5.0 and six months after that it was 5.3 so I had another negative biopsy.

My PSA then declined into the 4.* range where it stayed for 4 years. My urologist attributed the elevated PSA to BPH which was starting to be a problem. I later learned that I had changed labs and that different assay methods give different results, and that was probably what caused the reduction. But, whatever the number was, it wasn't rising!

In 2004 I changed labs again (but still didn't realize it was an issue) and my PSA shot up from 4.9 to 9.0 in one year! The retest was 9.4 but the DRE was normal. I was dealing with an enlarged prostate and doing alot of traveling so I decided to decline the biopsy. In June of last year my PSA hit 10.1 and finally agreed to another biopsy which was positive in less than 5% of the cores. I had a robotic-assisted RP 7/30/07 and so far everything is going well.

OK, so now you're thinking I'm nuts for not getting the biopsy sooner, and maybe I was. But I had been researching PC for many years and was getting regular PSAs which leveled off below 9.0 after that big jump. It was a form of 'watchful waiting'. Also, some people just produce more PSA than others and I assumed, with the cautious blessing of my urologist, than I was one of those people. In other words, my 9.0 was equivalent to a 5.0 in a 'normal' person.

In 1998 it was assumed that PSA's below 4.0 were not due to cancer, and that those from 4.1 to 7.0 were in a gray area. That's why I wasn't rushed into a biopsy after my first test. Anymore, probably due to fear of malpractice, urologists push biopsies on men with PSAs in the 2.* range.

Take the above for what it's worth to you. My only suggestion is to find out if they tested Free PSA, which might help you understand better where you're at. (My free PSA was 11%. My current PSA is .004 )

Best of luck to you!

 
Old 07-22-2008, 12:16 PM   #8
Senior Veteran
(male)
 
Join Date: Nov 2007
Location: Annandale, VA, USA
Posts: 1,730
Blog Entries: 3
IADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB UserIADT3since2000 HB User
Re: Hss anyone had constant elevated PSA levels that wasn't cancer?

A lot of important points have already been covered, so I'll just toss in a few fresh ones.

That new PSA threshold of 2.5 stems from work by one of the leading surgeons in prostate cancer who is also one of the leading researchers behind the original approval of the PSA test, Dr. William Catalona, MD. His team's research showed that a certain number of cancers were missed if the threshold was 4.0, but that you caught virtually all that were important at a threshold of 2.5.

However, I personally have not been too impressed with the value of lowering the threshold. That's because - this is from memory - you detect about 15% more cancers, but only 15% of them are aggressive. Well, 15% of 15% is 2.25%, a pretty small percentage. The question you get is whether it's worth doing a lot more biopsies to catch 2.25% of cancer that you would probably catch a little later without doing the extra biopsies. That's a judgment call, and I think the jury is still out.

In addition to the free PSA test that Kemahsabe mentioned, the PCA3Plus test is proving very useful, especially men who have signs of prostate cancer but negative biopsies. Its results can go a long way in helping a patient and doctor decide whether another biopsy is needed or not.

I just responded in another thread to Rock51 that at this time it looks very unlikely that a biopsy will cause a significant spread of prostate cancer (the needle tracking issue).

Jim

 
Old 07-24-2008, 07:04 PM   #9
Junior Member
(male)
 
Join Date: Mar 2008
Location: palos hills ill usa
Posts: 44
csyleen HB User
Re: Has anyone had low FREE PSA levels & High PSA that wasn't cancer?

I'm updating my post. My PSA was 4.7 and I just got my Free PSA test results and they were 13.1 %. So it looks like I will be getting a biopsy next week. Just wondering if anyone has had a low free PSA that wasn't cancer.

Last edited by csyleen; 07-24-2008 at 07:08 PM.

 
Closed Thread

Similar Threads
Thread Thread Starter Board Replies Last Post
My PET Scan Results...can anyone advise? VegasQ Cancer: Cervical & Ovarian 4 10-23-2009 12:47 PM
elevated pth level with normal calcium kiki745 Endocrine Disorders 52 04-30-2008 05:33 PM
Has Anyone Had Elevated PSA Levels? builder Men's Health 5 12-22-2007 07:53 AM
elevated HGB & HCT pelchatk Blood and Blood Vessel 3 08-01-2006 09:54 AM
christy217 ( or anyone else WBC count and bruising ?'s) andreanna Cancer: Colon 6 07-12-2006 08:25 PM




Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is Off
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are Off




Join Our Newsletter

Stay healthy through tips curated by our health experts.

Whoops,

There was a problem adding your email Try again

Thank You

Your email has been added




Top 10 Drugs Discussed on this Board.
(Go to DrugTalk.com for complete list)
Casodex
Cialis
Cipro
Flomax
Levaquin
  Levitra
Morphine
Proscar
Tylenol
Viagra







All times are GMT -7. The time now is 10:40 PM.



Site owned and operated by HealthBoards.com™
Copyright and Terms of Use © 1998-2014 HealthBoards.comô All rights reserved.
Do not copy or redistribute in any form!