Thanks for pointing this out.
I just did a PubMed check (www.pubmed.gov, permitted here because it is Government sponsored) and got 65 hits. It looks to me that it is promising
but may take quite a while before (if) it is proven, approved, and marketed
. I looked at one very recent abstract of a Phase I trial - the kind that is done early on to clarify what dose level is tolerable, but I saw no Phase II work - mostly plenty of lab work that involved human tissue but not human beings. While PARP inhibition may have been identified in the 90s, it looks like not much work was done to develop it. Almost always Phase II trials are needed after Phase I trials, and then Phase III trials are needed after Phase II. Each time, results need to be published and reviewed. In the US, the next step is for the FDA to consider the drug for approval. That too takes time.
I'm doubtful that such an approach could make it from where it is now to market in two years or under. I suspect this is another example of the media misunderstanding medical research. Hope I'm wrong. Anyone have more insight about the timing for PARP inhibitors?
Jim
Linear Mode
