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Old 10-28-2010, 06:24 AM   #1
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What chances I have

I am 36 years old and my father is dealing with prostate cancer for now 17 years.

I was just wondering whether there is any study indicating the actual percentage chances for children (like myself) to have the same and any advices what to do.

Thanks in advance for any replies.

 
Old 10-28-2010, 06:01 PM   #2
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Re: What chances I have

Quote:
Originally Posted by phalouvas View Post
I am 36 years old and my father is dealing with prostate cancer for now 17 years.

I was just wondering whether there is any study indicating the actual percentage chances for children (like myself) to have the same and any advices what to do.

Thanks in advance for any replies.
Hi phalouvas, welcome to the site but I am not sure that welcome is quite the terminology I should use. I am also a relativly new comer to this forum having being diagnosed with early stage PC about 18 months ago at age 55and have found it extremly helpfull and there are several members on here that I am sure will be able to answer your questions in a much more informed manor than I would ever be able to, however you may find my story of help.
My maternal grandfather died of PC at age 66 in 1966, there was probably little treatment available then,his eldest son, my uncle died of it at age 65 about 15 years ago, he elected to have no treatment,my own father also died of PC at age 74 about 20 years ago. I am now the youngest on the family tree to have got PC. To partially answer your question I would have to say that family history has definatly got a lot to do with your chances and all the literature I have read would support this. My urologist asked me if I had any sons which I have not but my youngest brother does, my urologist sugested then that I should have a talk to my brothers (one 2 years older and one 2 years younger) and urge them to start having annual psa checks now and any sons they have should start getting tested at age 40. You seem to kind of fit into a similar situation as me only younger and not telling you what to do and knowing what I do now, if I were you I would start having annual psa tests in the not to distant future. I at this point in time am pleased that I started having them and I went from psa <1.0 to psa 2.8 in a six month period - only had it checked this close together as I was having a cholesterol problem and doc. was just checking how I was responding to lipitor.
Merv

 
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Old 10-28-2010, 08:35 PM   #3
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Re: What chances I have

Quote:
Originally Posted by phalouvas View Post
I am 36 years old and my father is dealing with prostate cancer for now 17 years.

I was just wondering whether there is any study indicating the actual percentage chances for children (like myself) to have the same and any advices what to do.

Thanks in advance for any replies.
Hi:

From Canada to Cyprus hello. I'm currently 65 and have had two episodes of recurrent prostate cancer in 07 and 09. Neither of my parents nor extended family members has experienced this kind of cancer. While I'm not a doctor I feel that I can offer advice of a general nature based on personal experience and extensive review of the literature relating to this subject. In North America they are screening some high risk patients at age 40 and checking their P.S.A. levels. Also I woul suggest that you ask your G,P, to do a digital rectal examination on you at your annual examination in order to determine whether or not he/she can feel and/or detect any abnormalities. Unfortunately I don't know percentages off the top of my head; however, the fact that your father has prostate cancer would probably elevate your risk profile. Keep on top of the situation and let me wish you good luck.

 
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Old 11-22-2010, 07:21 AM   #4
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Re: What chances I have

Quote:
Originally Posted by phalouvas View Post
I am 36 years old and my father is dealing with prostate cancer for now 17 years.

I was just wondering whether there is any study indicating the actual percentage chances for children (like myself) to have the same and any advices what to do.

Thanks in advance for any replies.
Hi phalouvas

Rebelone above has given you an excellent example of prostate cancer running in the members of the same family. Surely you are doing well in discussing the matter now at your young age.
According to the Cancer Research UK, there is some evidence that suggests that prostate cancer can run in families. They say, as I quote here “……If you have a relative diagnosed with prostate cancer you are at higher risk compared to the general population. If your father had prostate cancer your risk is 1.5 times higher. If you have a brother with prostate cancer, your risk is higher, at just under 3 times the average risk.
The age your relative is diagnosed with prostate cancer is also a factor. If they were diagnosed before the age of 60, this increases your risk by about 4 times the average. And if you have more than one first degree relative diagnosed with prostate cancer (at any age) your risk is also about 4 times the average. A first degree relative means father, brother or son….


Of course these are only probabilities of having PC, bud the research is done based on real data, and surely many in the same family will never get it. My son, just turned 40, had his first PSA test on his birthday. He is in the same probability scale of high risk to get prostate cancer as you.

I was diagnosed with PC when I become 50 eleven years ago (my PSA was 22.4) and by doing some back calculations I now believe that the cancer has shown its “face” when I was 45/46 years old.
Hopefully you and my son will never experience such disease; however you should be ready to prevent any advance of the “bad guy” in time.

Wishing you the best,
Baptista

 
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Old 11-26-2010, 02:55 PM   #5
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Re: What chances I have

Hi phalouvas,

I hope you are still following your thread. I believe you are the first person from Cyprus to participate on the board, and that makes your post especially interesting for me as my wife and I lived a few miles south of Nicosia from 1969-1971. We have many fond memories of your island. Our older son was born in a clinic not far from the south end of Ledra street, just outside the wall.

You wrote, in your first post in this thread:


Quote:
Originally Posted by phalouvas View Post
I am 36 years old and my father is dealing with prostate cancer for now 17 years.
Good for your dad! Your statement makes an important point: prostate cancer is typically slow growing, and we have technology that is effective in controlling or curing the disease for the vast majority of us.

Quote:
I was just wondering whether there is any study indicating the actual percentage chances for children (like myself) to have the same and any advices what to do.

Thanks in advance for any replies.
You have already had several sound and helpful responses. If you want to look at summaries of findings from actual research, you can go to a site we can mention on this board because it is Government sponsored, known as PubMed, which stands for Public Medicine: www.pubmed.gov . You can search using a search string like this one (without the quotation marks): " prostate cancer AND risk of diagnosis AND inheritance". I just did that and got 36 hits. You can see a summary of the paper (if there is one) by clicking on the blue hypertext title, all for free. Sometimes the whole paper can be read for free. Much of the content will be highly technical, but often the key parts are understandable to the general public.

Please also keep in mind that much of the research comes from North America and northern Europe, rather than the Mediterranean. That is likely important, as both geography and diet appear to influence the risk of prostate cancer. It appears that vitamin D is important, and you should be getting plenty on Cyprus, unless your skin is dark or you use a lot of sunscreen. Also, the "Mediterranean" diet appears to be among the best for reducing the risk of prostate cancer, so you probably also have that in your favor.

Here's a very important point to keep in mind about research: genes are like a light switch; some of us have certain genes predisposing us to having prostate cancer, and some of us do not. However, it appears we can do a lot to turn the switch on or off! For example, in a very large study observing prostate cancer among doctors who kept track of their health over many years, doctors who consumed ten or more servings of lycopene (mainly from cooked tomato foods or juices) had a 41% lower risk of prostate cancer than doctors with low consumption. Doctors consuming a lesser amount - 4 to 7 servings per week, had a lower but still substantial benefit, about 20% lower risk, as I recall the numbers. That's not a guarantee that cooked and processed tomato products will lower risk, but it's encouraging. Also, that's just one food item, and other items may have similar and independent impacts on risk.

Here are a couple of good books that cover some of the nutrition and other lifestyle tactics to help reduce risk of getting the disease: "Beating Prostate Cancer: Hormonal Therapy & Diet," by Dr. Charles "Snuffy" Myers, MD, and "Invasion of the Prostate Snatchers," by Dr. Mark Scholz, MD, and Rallph Blum. They might also be interesting to your father. In addition, for men who are at significant risk, there are some generally mild medications that help reduce the risk of the disease; in the US they are known as finasteride and Avodart. However, they can affect the ability to father children, and for some men they reduce sex drive (while increasing it in others).

Take care,

Jim

 
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