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Old 04-20-2011, 01:56 PM   #1
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Irv's PSA is down to 0.22!!!

This news seemed deserving of a new thread to me. After his RP in November, his post op PSA came in at 1.12 and went to 1.19 within a week and then to 2.19 at the one month mark. In less than 2 months on ADT3, he's down to 0.22! He's also been exercising at the gym almost daily and has lost over 20 lbs. He looks and feels great!

Please join me in wishing him continued success.

So, does this seem like a quick decline? Would this be indicative of triple blockade vs. single blockade? Would there be a difference in time for PSA decline? Would love some input. So far, things are looking up. I'm guessing in another month, his PSA will be undetectable.

Rhonda

 
Old 04-20-2011, 02:02 PM   #2
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Re: Irv's PSA is down to 0.22!!!

Congratulations.
Finaly your peace of mind is set. I hope that number gets to remission the soonest and it is kept there forever.

The best to Irv

Baptista

 
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Old 04-20-2011, 03:45 PM   #3
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Re: Irv's PSA is down to 0.22!!!

Hi Rhonda and Irv,

Heartiest congratulations!!!


[QUOTE=honda50;4735883]This news seemed deserving of a new thread to me. After his RP in November, his post op PSA came in at 1.12 and went to 1.19 within a week and then to 2.19 at the one month mark. In less than 2 months on ADT3, he's down to 0.22!"

That's clear evidence that the triple blockade is working well, and a continued steep decline is extremely likely.

Quote:
He's also been exercising at the gym almost daily and has lost over 20 lbs. He looks and feels great!
I am so convinced that aerobic and strength exercise, as well as diet and nutrition, is the magic key to being able to minimize side effects and maximize health while on hormonal therapy. When I started on this course in late 1999, I was still working at a mentally demanding job and figured that the therapy would set me back healthwise. I did not know then that I would work for another five years before leaving of my own choice, feeling great, and not forced to retire by the disease. It turned out that I was healthier than almost all of my coworkers and rarely missed a day for any kind of illnesss.

Quote:
Please join me in wishing him continued success.
Amen to that!

Quote:
So, does this seem like a quick decline? Would this be indicative of triple blockade vs. single blockade? Would there be a difference in time for PSA decline? Would love some input. So far, things are looking up. I'm guessing in another month, his PSA will be undetectable.

Rhonda
I believe that many docs who are not familiar with the awesome power of well-done hormonal therapy would consider it a quick decline. It is actually probably fairly typical for lower- and intermediate-risk patients who have recurred (and are therefore higher risk than other patients with low-risk characteristics) for triple therapy. Irv will probably have his PSA drop below 0.05 in a few more months. Usually that takes around three to six months for patients on triple blockade.

Some patients on single and double blockade are able to get their PSAs to somewhere below .1, and some even make it to below 0.05. However, I'm convinced PSAs drop at least as fast and more deeply on triple blockade than most patients will achieve on double and single blockade. My own PSA was leveling out at around .6 on double blockade, and it took triple blockade to cause it to continue to drop to <0.01. I've learned of some higher risk patients who have trouble getting their PSAs below 1.0 on single and double blockade. Also, there's some solid evidence that PSAs stay lower longer after triple blockade with finasteride or Avodart continued as maintenance during the off-therapy period. As you can see from the graphs in the Primer, more than half the patients who had recurred after surgery, radiation or both, were able to remain on vacation from the heavy-duty drugs at the five year point.

One of the leading doctors in hormonal therapy talked to a nearby support and education group last Saturday, and I had a chance to tell him about a patient I knew of in Toronto who had had a hard time getting on triple therapy. I mentioned your tangle with Dr. Tannock, and he leaned back with a laugh and said he knew or knew of Dr. Tannock and that he hated triple blockade! He also joked that Dr. Tannock was negative toward many unstandard approaches. He said he paid attention to what the good doctor said as you would probably be on the right path if you did the opposite! While that sounds harsh, he said it with humor, and I sensed he also had a good deal of respect for Dr. Tannock, though not in the area of hormonal therapy.

Take care and keep up those wonderful results!

Jim

 
Old 04-20-2011, 06:07 PM   #4
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Re: Irv's PSA is down to 0.22!!!

Great news, Rhonda! May his PSA stay low forever!

 
Old 04-20-2011, 08:18 PM   #5
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Re: Irv's PSA is down to 0.22!!!

I'm so appreciative of all of your good wishes that I could almost cry.....just because I'm so touched....and also because Jim, you mentioned Irv's case to a doctor who specializes in hormone therapy. Thank you. I feel such a connection from across the miles which means more than you could ever know.

While we were on our cruise, one of our table mates is a cancer survivor and she swears by a natural product called Oncolyn. Have any of you heard of it? Supposedly it works for all kinds of cancer. This woman believes she has had a lot of success with it. Let me know if you've ever heard of it or have any thoughts on it.

Regards, Rhonda

 
Old 04-21-2011, 12:12 PM   #6
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Re: Irv's PSA is down to 0.22!!!

Hi Rhonda,

Thank you for your response - it touches me to know that I was able to help. I found out a little about Oncolyn and will insert that in green below.


Quote:
Originally Posted by honda50 View Post
...

While we were on our cruise, one of our table mates is a cancer survivor and she swears by a natural product called Oncolyn. Have any of you heard of it? Supposedly it works for all kinds of cancer. This woman believes she has had a lot of success with it. Let me know if you've ever heard of it or have any thoughts on it.

Regards, Rhonda
I have never heard of it, but I searched PubMed (Public Medicine at www.pubmed.gov, a site we can use on this board because it is government sponsored) and got just one hit related to aging in mice - not too helpful, unless you are a rat or mouse. I looked again for available papers, including informal stuff, and found many, but most in Chinese and many involving research in rats or mice. There were seven pieces in English that did not include mice or rats. I learned that Dr. Arthur Djang, MD, MPH, PhD developed this mix of herbals, a proprietary formula possibly involving green tea, grapeseed extract and other elements. I also checked information from a doctor who is expert in quack medical treatments, drugs and supplements, but he did not have anything to say about it, so that's a mark on the good side, but far from a positive endorsement.

It's good that your cruisemate found this to be helpful, but it is impossible to know whether it really has any value for prostate cancer at this point.

Take care,

Jim

 
Old 04-21-2011, 12:35 PM   #7
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Re: Irv's PSA is down to 0.22!!!

Quote:
Originally Posted by IADT3since2000 View Post
Hi Rhonda,

Thank you for your response - it touches me to know that I was able to help. I found out a little about Oncolyn and will insert that in green below.


Jim, you've been able to help in more ways than I could possibly find a way to thank you for.

I have never heard of it, but I searched PubMed (Public Medicine at www.pubmed.gov, a site we can use on this board because it is government sponsored) and got just one hit related to aging in mice - not too helpful, unless you are a rat or mouse. I looked again for available papers, including informal stuff, and found many, but most in Chinese and many involving research in rats or mice. There were seven pieces in English that did not include mice or rats. I learned that Dr. Arthur Djang, MD, MPH, PhD developed this mix of herbals, a proprietary formula possibly involving green tea, grapeseed extract and other elements. I also checked information from a doctor who is expert in quack medical treatments, drugs and supplements, but he did not have anything to say about it, so that's a mark on the good side, but far from a positive endorsement.

It's good that your cruisemate found this to be helpful, but it is impossible to know whether it really has any value for prostate cancer at this point.

Take care,

Jim
Thanks for looking into that for me, Jim. I also found that one article on Pubmed, which, of course, means nothing. The woman that I spoke to told me about somebody she knew who was so sick and dying with cancer and then, after taking Oncolyn, she went into remission and has been good since. She also mentioned something about somebody with prostate cancer taking it. I wish there were more information about it, but it sounds like something which would be worthwhile considering.

Rhonda

 
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