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Old 02-19-2012, 10:45 AM   #1
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What does "heterogeneous marrow signal intensity" mean?

Sorry, I'm sure I'm over reacting - still waiting for my biopsy. I had an MRI because my last biopsy was negative and they've found two small areas to target for the next one.

One question I have, on the MRI it says "Pelvic Bone Marrow: There is heterogeneous marrow signal intensity in the bones of the pelvis. There is degenerative disc disease at L5-S1." Is that normal? What does heterogeneous marrow signal intensity mean?

The MRI goes on to say...

No evidence of extracapsular disease.

So I'm hoping the bone thing is normal since they say there is no evidence of extracapsular disease - wouldn't that be correct?


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Old 02-20-2012, 05:52 AM   #2
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Re: What does "heterogeneous marrow signal intensity" mean?

Hi jupaul,

You asked whether "degenerative disc disease at L5-S1" is normal. It is not normal, but it is not prostate cancer either. That finding is worth discussion with a doctor specializing in bones.

I'm not sure what "heterogeneous marrow signal intensity" means; it may be normal. Perhaps someone else knows. You could call the doctor and ask.

Regarding "extracapsular disease," I believe that refers just to the area just beyond the capsule of the prostate rather than the whole body beyond the prostate. Of course it's a good finding as it suggests the capsule has not been penetrated by the cancer. (Cancer can also hitchhike out of the prostate via the lymph and blood systems.)

Take care,


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