That DHT is much above what it should be for a patient on Avodart as part of triple blockade. The units in Irv's version of the DHT test are different from mine, but here's what my doctors and I look for: a DHT of 5 or lower with a reference range of 25 - 75 ng/dL (nanograms per deciliter).
Irv could still have benefited from other influences of Avodart, such as reducing the blood supply to the cancer. However, he may be one of the small proportion of patients who does not get much benefit from Avodart (dutasteride) because of his genetic makeup. I've read that such patients often get the benefit they are looking for by switching to finasteride, the generic version of Proscar.
If extra blood was taken and the DHT test can be rerun, that would be a good idea. A fresh test could also be done. If the initial result is confirmed, then I believe the doctors I have been following would switch Irv to finasteride for his "off-therapy" vacation period from the Lupron and bicalutamide.
Irv has had a fine PSA response, and with good control of DHT he should get a long vacation period, hopefully indefinitely long. The Scholz, Lam, Strum and colleagues team have had an informative paper published about this. Good luck in sorting this all out and getting that DHT down.
Regarding cholesterol, is Irv taking a statin drug?
Originally Posted by honda50
Irv has gotten all of his blood work results back and all looks good. Even his bone scan came back NORMAL! We were thrilled! His vitamin D levels are good, his cholesterol levels are slightly off but nothing terrible, he isn't anemic and his sugars are good too! His testosterone is 1, with the normal range being between 6 and 27.
My only question is regarding the DHT level. The normal range is between 860 and 3400 and Irv's is 1702. Yet he's on Avodart. I was expecting it to be lower. It's well within the normal range and that concerns me as DHT is more potent at fueling the cancer from what I understand. Is this normal for somebody who's on triple blockade hormone therapy?