I had RPP in December of 2011. I am a 52 year old and had open surgery done at the Huntsman Cancer Institute. There was not nerve sparing and the seminal vesicle was taken as well. Pathology stayed the same as it was diagnosed as a Gleason 4+3. 10% of my prostate was involved and ended up being graded as T2c. I was well aware that I would have ED after this surgery but it was the best chance, in both mine and my surgeons opinion to be cured. I asked for lessons for injections just two months after my surgery because I wanted to get back to being able to make love to my wife as quickly as possible. The last time that we had done it was in October of 2011 because of all the BS that happens with having a 12 core biopsy done.
Now that you have the history lets get down to what the thread is about. My Urologist started with a mix of 150/5/50-5ml Trimix. He did the first two injections (a week apart)and I have done all injections since. At first the thought of sticking myself in my penis was dreadful to say the least but that feeling is easing up after doing it now about 5 times myself and also educating myself through other sites that there is almost no real danger to yourself if you follow simple instruction from your doctor.
The Urologist started out with .015cc of the mix, so using a 1/2 ml cc with a 8mm (5/16s of an inch long) 31G needle, the cylinder was filled to 15.
The above amount was not sufficient to give me a firm erection. It gave me what I would classify as getting half way there. It started to harden but would not be able to penetrate. This was my first lesson and visit two months after surgery. A week later I went back and the urologist filled the syringe to 23. This produced a little firmer erection but still not enough to be able to penetrate. My Urologist wanted to schedule another appointment but I decided that with my copay being $80.00 each time that I had been "trained" enough and that I could carry out the rest of the experimentation at home. I waited three days and filled the syringe to 28 and was able to get a firm enough erection to finally penetrate. My wife was really happy but I, while being glad to see a firm penis, absolutely hated the achy feeling that I was having since achieving an erection. I noticed this feeling with the first two shots but figured it may go away. My erection lasted about an hour and the achy feeling stayed until the erection went away. 3 more times of injections and making love to my wife but finally deciding that this achy feeling really sucked! I have been reading up on Trimix and Bimix since I was first diagnosised with prostate cancer and have since found out that the "Achy" feeling is caused by the drug Alpostradil aka Prostaglandin E1 (PGE1)
I am going to start experimenting with possibly a bimix or a very light dose of Alpostradil and trimix. Depending on the recommendations of my Urologist. I have read that Bimix does not work on a lot of patients so I do not know what to expect. I will report back my progress through this maze of aftermath from RPP and the road to recovery when the prostate and nerves are gone. Cheers!