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Cancer: Rectal & Anal Message Board
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Old 09-08-2010, 07:59 PM   #1
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Join Date: Sep 2010
Location: san francisco CA USA
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smile3 HB User
Xelox (Capox) vs Xeloda (capecitabine) alone

Hi,

Does anyone know how much more effective adding oxaliplatin to capecitabine would be as treatment for systemic control of rectal cancer cells that might have escaped before pre-op chemoRT and surgery?

I had T3N0M0 rectal cancer several months ago and this was 1) shrunk by radiation and Xeloda and 2) removed by the usual total mesorectal excision. Now I am due for systemic treatment with Xeloda with or without oxaliplatin.

I'm wondering how much oxaliplatin would increase my chances for disease-free survival, whether the risk of oxaliplatin would be greater than its benefit (for a woman in her 80's,) and whether I could just go back to Xeloda alone if things go horribly wrong.

Thanks for listening!

Smile3

 
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Old 02-26-2011, 01:58 PM   #2
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Join Date: Feb 2011
Location: tel aviv , israel
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danielschmidt HB User
Re: Xelox (Capox) vs Xeloda (capecitabine) alone

Quote:
Originally Posted by smile3 View Post
Hi,

Does anyone know how much more effective adding oxaliplatin to capecitabine would be as treatment for systemic control of rectal cancer cells that might have escaped before pre-op chemoRT and surgery?

I had T3N0M0 rectal cancer several months ago and this was 1) shrunk by radiation and Xeloda and 2) removed by the usual total mesorectal excision. Now I am due for systemic treatment with Xeloda with or without oxaliplatin.

I'm wondering how much oxaliplatin would increase my chances for disease-free survival, whether the risk of oxaliplatin would be greater than its benefit (for a woman in her 80's,) and whether I could just go back to Xeloda alone if things go horribly wrong.

Thanks for listening!

Smile3

 
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