Biclonal Igm kappa. Band 1 0.17, Band 2 0.17, Alph 1 0.20, alph 2 0.52, drop of Folate to 2.2, ESR 35, RBC 3.48. I had AVR 1997, stent left Iliac DES, Plavix since Oct 2011, w/Aspirin 325mg, Coumadin for AVR, concerned about VTE, even with the blood thinners. Taking 1mg Folic Acid and 1500mg Niacin to replace Simvastatin (had well controlled Statins B4) Primary doctor VA. Male, 77 yrs. INR dropped to 1.8 from 2.7 in 4 weeks for no reason, unless Mgus side effect. ???
M-PROT. Test Persistent monoclonal protein IgM kappa band=o.25 g/dl in the gamma region. I went to Cancer/Kidney doctor, he ran blood test, bone x-rays, I can have bone biopsy, but nothing really indicates the need. I said maybe in 6 months or if symptoms/numbers go up. VA did lab work on the M-Protein. So I guess it's MGUS. RBC is 3.63 range 4.44-6.1, have been low for years after AVR in 1997. I will look at past labs. IgM increase has taken a long time. Loss of appetite appears to be symptom. Mine is great. BMI 31. Thanks.
Thanks for the information. My IgM levels (254) have slowly been climbing, and my IgG levels (565) are slowly falling. Appetite so far is good. I declined to have the bone marrow biopsy, I said not enough M-Proteins I wanted to wait another 6 months or a year, sooner of course if the M-Proteins spike up. I keep having low vitamin D levels, given a prescription vitamin D. Now when the vitamin D levels are low the bone pain is unbearable before I had moderate pain when it was low. Every now and then I will have a day where I am very tired. My mother died from Multiple Myeloma, so I can not ask her questions.
I have the last 15 years of labs, IgG stays around 791 to 962 currently 818, IgM on high end 303 to 448 currently 354. Cancer doctor says I have some M-Protein 0.4. VA doctor said same thing. He seem little upset that I had went to Cancer doctor. My heart doctors' dad was taken by Myeloma, he referred me to his dads' doctor (the cancer doctor) Good recommendation. My understanding of the protein is that there are serveral reasons other than Myeloma for having the readings' resulting in the finding of MGUS. I have been told, make sure you have a medical doctor follow your MGUS. HUH, sort of goes without saying.
Good luck, I think life is knowledge, learning something every day.
There is nothing wrong in seeking a second opinion when you may be dealing with something serious. Thanks for the update. Yes I knew that other causes can raise IgM levels, also knew having high levels of M proteins does not necessary mean it is Multiple Myeloma it could be another cancer. I keeps records of everything learning as I go ask questions when I need to. Since my vitamin D levels have been slightly raised some of my bone pain has disappeared.
The Following User Says Thank You to bestoldies04 For This Useful Post: WD34 (08-14-2012)