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Old 08-16-2012, 08:08 PM   #1
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Myeloma question

Hi,

I'm hoping I"m posting in the right place. Without going into great detail, I've been dealing with issues initially thought to be MS. I've been told it's not MS, but that something systemic is going on and I'm waiting for tests to confirm small fiber neuropathy.

In the report I received today, it states:

"The immunoglobulin profile was normal aside from a high Lambda at 6.61 (normal 2.43-5.91) and thus a low kappa/lambda ratio of 1.30 (normal 1.54 - 2.78)

This is from a Canadian hospital, so not sure if the units would be the same in the US. When I tried to read about kappa/lambda I keep bouncing onto myeloma.

Any idea what this means??

Thanks for any suggestions.
Gully

 
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Old 08-16-2012, 09:21 PM   #2
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Re: Myeloma question

Myeloma is a bone marow problem where plasma cells that normally produce antibodies start making excess light chain proteins, of which there are 2 types, kappa and lamda. If one is produced in excess, it throws off the ratio of the two. So it appears you are producing too much lamda protein, and the significance of that will need to be determined. This is sometimes called monoclonal gammopathy, and mild elevations can exist for years in some people without causing disease, and requires monitoring but nothing further. Your Dr may refer you to a specialist for further testing or monitoring (a hematologist). I would wait until you have a chance to talk about this more with your Dr. and review results of other tests you may have had to shed some light on it.

 
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Old 08-17-2012, 03:32 AM   #3
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Re: Myeloma question

Thank you ladybug. I see my Dr. Sept 10th, but I'm well seasoned in the waiting game.
Have a great day.

 
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