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Celiac Disease Message Board
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Old 07-28-2009, 02:49 PM   #1
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Celiac's or...?

Hi.

Here are my symptoms:
Weight Loss
Arthritic Pain
Infrquent passing of stool (once every four days)
Loose, soft, pale stool
Gas/Flatulence
Low Cholesterol
...and some other minor things.

Anyways, my doctor did screening for Celiac's disease and here are the results:

GLIADIN ANTIBODY (IGG) Normal Range >11 Result: 11 (Abn:H)

GLIADIN ANTIBODY (IGA) Normal Range >5 Result: >3

RETICULIN IGA SCREEN: Negative

TTG ANTIBODY IGA Normal Range >5 Result: >3

TTG ANTIBODY IGG Normal Range >7 Result: >3


Due to my symptoms and the minor elevation of the IGG antibody, the doctor is recommending a endoscopy. From what I have read, IGA is more specific while IGG is more sensitive. What exactly does that mean and how does it pertain to me? If I do not have Celiacs, could the IGG antibody be a sign of a different problem?

Thanks

 
Old 07-30-2009, 04:25 PM   #2
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Join Date: Feb 2007
Location: Florida
Posts: 1,453
AuntieLeela HB UserAuntieLeela HB UserAuntieLeela HB UserAuntieLeela HB User
Re: Celiac's or...?

High sensitivity means the test is good at finding sick people and correctly identifying them as such.

Highly specific means the test can weed out healthy people, or folks with "false positive" results.

Your IgG is borderline. It could be inflammation from something else - there's many different disorders that can slightly elevate IgG - it might even be normal for you.

But then again, your symptoms are strongly suggestive of Celiac and a positive result, even a weak one, on one of the Celiac Panel tests means an endoscope.

Make sure they take at least 6 biopsies - and don't believe them if they tell you they could "tell just by looking" that you don't have Celiac - the damage is often microscopic and can't be seen with the naked eye. (I ended up having to have endoscopy three times in five years because of bumbling docs who didn't know how to properly dx Celiac )

 
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