CFS/ME is a very real condition which needs much research done - which unfortunately doesn't unfortunately happen. My daughter was a very good tennis player just 13 months ago and loved playing the game. Since having CFS/ME she is unable to play which is devastating for her. Her legs are too weak. Most CFS/ME sufferers get quite down from having their condition (who wouldn't!) and people then think that some depression is causing their condition - which is so wrong. Thanks for asking this - it is always good to explain that depression is a very different thing from Chronic Fatique.