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Old 07-03-2013, 03:04 PM   #1
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Mylan Fentanyl Transdermal Patches

I prefer Mylan patches because of their small size, relative to competitive products such as those made by Apotex. I was having great difficulty removing the residue left behind by removing the patch. I tried olive oil, and soap and water, but neither worked, because Mylan uses a silicone-based formula instead of a mineral oil-based formula like other manufacturers - and scrubbing with the soap and water eventually broke through the skin, leaving raw patches that required that I move the patch site (note: I typically place the patch[es] on the side of my lower abdomen, directly across from my navel. While the manufacturer recommends placing the patches either on the upper arm or back, my experience is that they peel off either during activity or turning over in my sleep. Also, other patch manufacturers [fox example, Apotex] do recommend placing the patches on the abdomen as their first choice for location).

I called Mylan and left a VM for the Sr. Dr, Product Safety & Risk Management, who had a Mylan pharmacist return my call. The pharmacist said that Mylan had never performed any research on patch removal (!!!???!!!) and had no suggestions! I spoke with my local pharmacist, who recommended that I try nail polish removal (either acetone or non-acetone type). I tried both; neither worked but did cause a burning sensation on the skin.

This morning I tried WD-40 -- SUCCESS!!! I sprayed a small amount onto a paper towel and all residue came off immediately. I then used a washrag with soap and water to remove any traces of WD-40. All-in-all, it proved to be a quick, benign and pleasant experience.

I hope this helps!

Also, to the person reporting that they were still experiencing pain even though they were following manufacturer's directions for use of the patches, I also had the same issue, and found the following solutions from talking with a friend using the patches for cancer pain, as well as my pain management specialist: (1) even though the manufacturers say that the patches last 72 hours, is is a common experience that the patches in fact need to be changed every 48 hours; and (2) when first using Fentanyl patches, check back with your doctor every two weeks to adjust the amount of medication for effectiveness in treating YOUR pain (pain is a very individual experience). For example, I went from the original 50 mg prescription to 150 mg within 45 days of experimentation, and have been satisfied with 150 mg ever since (about six months so far).

 
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Old 07-04-2013, 01:43 PM   #2
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Re: Mylan Fentanyl Transdermal Patches

Hi-

I too use the fentanyl transdermal system with excellent results, but I am using the Brand name-Duragesic. Duragesic is also the maker of the generic patch-Sandoz.

You may not be aware, but Mylan contains a significant less amount of fentanyl in their patches.

For example; Mylan's 100mcg patch actually only contains 10.20mgs of fentanyl; Duragesic and Sandoz 100mcg patch both contain 16.8mgs of fentanyl. Mylan's 75mcg contains 7.65mgs of fentanyl, Duragesic n Sandoz 75mcg contains 12.6mgs of fentanyl. Mylan's 50mcg patch contains 5.10mgs of fentanyl, Duragesic n Sandoz 50mcg patch contains 8.4mgs of fentanyl. Mylan's 25mcg patch contains 2.55mgs of fentanyl, Duragesic n Sandoz 25mcg patch contains 4.2mgs of fentanyl.

I experience very good pain control using the brand name Duragesic(I have also used the Sandoz with good pain control also).

Both the Duragesic and Sandoz when removed leave no type of adhesive residue either, so no need for the WD40(yikes!)

Hope this info helps.
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Old 07-05-2013, 10:00 PM   #3
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Re: Mylan Fentanyl Transdermal Patches

Dear anyhelp, I use mylan also. After soaking in hot bath for 15 minutes or so the glue comes right off of me by just pulling it with my fingers or washcloth. I asked pharmacists twice about the difference in the amount between duragesic & fentanyl & i was told no matter how much "extra" in patch it comes out at the exact same rate & that "extra" is just left in patch when thrown away. On the 100 mcg patch at 100mcg/hour thats 2400 mcg per 24hours of fentanyl excreted, multiplied by 3 days is 7200 mcg or 7.2mg used out of 10.2 mg available in each 100mcg patch. I havent been able to tell a difference but change every 48 hours. Do you have to wear multiple patches bc i have had the 100mcg for a long time & i dont know if they have started making a patch higher in dosage than a 100mcg?

Last edited by gmak; 07-06-2013 at 07:19 AM. Reason: wording

 
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Old 07-06-2013, 01:26 AM   #4
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Re: Mylan Fentanyl Transdermal Patches

Dear Anyhelpok=

I am pretty sure if you were to try the Brand name form of the fentanyl transdermal system-" Duragesic" or even it's generic counterpart, "Sandoz", made by the same pharmaceutical Co.-you just may not find the need to use 150mcg's of the drug.

Pharmacists who claim that all Fentanyl patches release the fentanyl medication at the same rate is nothing short of ignorance on their part, though this is only my Doctor's opinion. There are many factors that come into play; particularily the actual mg amount of FENTANYL in the patch.

Take the Brand name "Duragesic" and it's(generic), "Sandoz", at the 100mcg strength, both(matrix) contain 16.8mgs of the active ingredient-FENTANYL- , at peek these two 100mcg patches should be(according to the accompanying info pamphlet) releasing 100mcgs of fentanyl per hour.

I submit that the brand name "Duragesic" and it's generic form "Sandoz" absolutely does. I am saying this due to the fact that I suffer intense, intractable chronic pain-S/P traumatic injuries-I am getting really good relief at this dose, and this was much to my amazement! Between my Neurosurgeon and PM Specialist I have been tried on sooo many different medications to help this severe pain, and then we tried the fentanyl patch, in combination with other adjunct meds. After about 5 wks of titrating and at 100mcgs, Duragesic, changing every 48 hrs I found decent relief finally!! I literally sat down and cried, not from pain for once, but because I was so grateful for the relief of relentless agony and the insomnia. It's not pain free, by any stretch of the imagination, but with the combo of my meds including the Duragesic patch I am getting up to 50% relief sometimes! To me this is great.

The generic fentanyl (matrix) patch-MYLAN-also 100mcg strength; however contains only 10.2mgs of the active ingredient fentanyl, and claims to; according to their info pamphlet to release 100mcgs of fentanyl per hour at peek. Being that Mylan's 100mcg patch contains only 10.2mgs of FENTANYL; it is NOT releasing 100mcg's of Fentanyl per hour, not at peek, not at all. Very misleading.

This is only my humble observation.

I have even tried all the other generic fent patches prior to Duragesic and Sandoz-infact I know others who also use the patch, and if you have used the Mylan and the Duragesic, it is simply impossible not to notice the difference-that is why I don't use the Mylan patch after trying the Sandoz and Duragesic-the difference AND the QUALITY of the pain relief that I need and am desperate for; is quite noticeable. It helps the awful pain-related insomnia too as I previously mentioned!

If your Ins won't allow you to get the Brand name-"Duragesic" (my Doctor had to get it pre-authorized for me)-get the "Sandoz" as they are the generic form made by same pharmaceutical Co. as the brand name "Duragesic" and contains the SAME AMOUNT of fentanyl as the "Duragesic", mcg to mg.

Call your pharmacy and ask if they can at least get you the "Sandoz"; if your ins won't auth the "Duragesic". If your usual pharmacy can't or won't get the "Sandoz" generic for whatever reason; it would be worth it to call around to other pharmacies to see if they can get it for you; and I'm pretty sure your doctor will make an exception about using the same pharmacy for all Rx's from him/her, if you explain your normal pharmacy can't get it for you. I believe you will be happy if you can at least get the generic form of "Duragesic"(Sandoz). The matrix strip is small and just as easy to accomadate as the Mylan, it's just that the Sandoz(like the (Duragesic) has significantly more fentanyl and quite noticeable in the pain relief.

If you do a search on this forum; you will find a lot of discussion on this very same topic.

I speak from my own experiences with these patches, and I have been stable on them at the same dose for almost 3yrs. Trust me when I say: My injuries left me with terrible, intractable pain-and if Mylan gave me better pain relief, I certainly would be using them, you see I am not impressed by what anyone says or claims-I can only go by what gives ME the best pain relief; PAIN, as most folks know, is SUBJECTIVE-so if you suffer from intense pain and the relentless insomnia that goes with it(in my case anyhow) due to the pain-I highly recommend you try the Brand Name Patch "Duragesic"or it's generic; "Sandoz".

Good luck and I wish all CP patients the best pain relief possible.
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Last edited by BB07; 07-06-2013 at 03:55 PM.

 
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Old 07-06-2013, 06:21 PM   #5
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Re: Mylan Fentanyl Transdermal Patches

Dear any, Of course the brand may help you more because it does help different people different ways & i wish mylan or duragesic took all the pain away but i have to take bt & other adjunct medicines too just to get it to a five. I called my pharmacist & he is going to research them both again tonight & if there is any advantage to me by wearing the brand he will call me. I wasnt disputing what helps someone else or what their dr told them just my own experience & everyone is different, this is unique to each person & the good great part is one works well for one person & another kind helps me but both of us get relief! I hope that you find that soon!

Last edited by gmak; 07-06-2013 at 06:33 PM.

 
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