doesn't do much for me (Dayquil) and Nyquil is no better, in fact it often keeps me awake. Of course they took the pseudophedrine out of their products, which is what would keep me awake. If I take any meds it's something like Advil Cold and Sinus. Generally I don't take many meds when sick. If I have trouble sleeping because of the congestion I take Sudafed or Afrin. Lots of sleep and drinking tea, that's my remedy..