Yaz has a form of estrogen in it, which makes it a "friendly" birth control pill for someone with depression--it's the ones that are progesterone only that can increase depression. It's not the diuretic that helps with depression, it's the estrogen. They just got FDA approval for it for PMDDs.
I thought Cymbalta was supposed to be less problematic with the "finale'" than most others. Wellbutrin--tried that for the same reason, but only 150 mg. I tried it on its own and also with Zoloft. No help at all. Psychiatrist said it needed to be at 300 mg. but there were things on the PI sheet that I didn't want to experience (tachycardia) so I didn't go higher. I hear that skipping a day of Cymbalta is or can be painful...maybe like Effexor? So meds "holiday" wouldn't work, for the "finale" issue I guess.