I was on zoloft for 4 yrs. MY side effects were: anxiety, indigestion, aggression, insomnia, etc. I just tried switching to serzone and it was much worse. I have now realized that zoloft was working better than I thought it was. Now I'm switching to Paxil because it is a cousin of zoloft, and other friends have had good results from it, and MAYBE the side effects will be less trouble- some. About weight gain, yes I've gained, but I'd rather feel better inside.
If you want to find out more about a particular med, and it's possible side effects, go to the library, find a "PDR" (Physicians Desk Referance) and look it up. Remember, the same meds affect different people differently. Good luck and please be an informed consumer on the meds issue, and any other for that matter. Bob