Depakote can have massive side-effects, many unpleasant ones, but it is probably very dosage-related. A small dose might work out OK, but it would never be my first choice as a patient (I have BPI). Unless you are truly bipolar, I think you have some friendler choices to explore with your doc. Depakote often causes weight gain, cognitive dulling, lethargy, just to name a few. (Remember, it was originally designed for epilepsy before it started being used for other disorders, so it targets different parts of the brain than a drug like Prozac.) Have you explored any of the benzodiazepines, like clonazepam? They're so calming, and clonazepam saved my life. Good luck.
Last edited by TinoRock; 11-07-2012 at 04:18 PM.