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Old 03-13-2001, 05:54 AM   #1
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chrismth HB User
Post Effect of diabetes med on other problems

Hi!

Since hypertension and elevated lipid problems can be associated with insulin resistance it would seem to me that treating a person with a drug that decreases insulin resistance like Actos might work as well as giving a person multiple medications for the other problems. I would think that when a person presents with these problems one of the first things they should do is investigate their blood sugar levels yet it didn't happen with me and I don't hear a lot of people taking about their glucose levels the way they do their cholesterol levels.

I have read that there has been a 70% increase in the cases of type II diabetes diagnosed in the past 10 years in the age group 30-39. That sounds pretty serious to me.

Chris

 
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Old 03-13-2001, 05:46 PM   #2
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Hi Chris, I agree with you. The MD's often just treat symptoms not the cause of disease. I have been reading the Dr Bernstein book and others lately. It seems to my if you "cure" or control the insulin resistance the colesterol and BP will take care of itself.
barb

 
Old 03-13-2001, 08:38 PM   #3
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Hypertension and high lipid levels are also two (2) risk factors for heart disease as well as diabetes.

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Old 03-14-2001, 04:45 PM   #4
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Hi Barb, Chris, and Ken,
___Although the published stats say that 60% of diabetics have high lipid numbers and risk CVD, I believe its closer to 90%. One of the clinical reports I've read stated that Avandia had antioxidant properties and was of benefit in preventing atherosclerosis. Since Actos is a glitizone also, I assume that it is of some benefit also. Unfortunately, it is terribly expensive, and with regards to my wife, its action diminished to nothing after about eight months. The only side effect was weight gain. One thing that has helped her a bit is the combination of chromium polynicotinate, and vanadyl sulfate. Chromium is necessary to the transport of glucose into the fat cells, while vanadium sensitizes the muscle cells to the transport of glucose. It's used by body builders to increase their endurance and glycogen storage in the muscles. No more than 10mg twice a day should be used.
___About 80% of the cases of hypertriglyceridemia (tg's over 1000) are common to the diabetic. In my wife's case, she has had as high as 6625mg/dl. Many complications occur because of high triglycerides. Any doctor that ignores them is ignoring something as bad as LDL's and VLDL's. When tg's are over 800 to 1000, small semi-translucent eruptions occur around the eyes, back of the hands and wrists, and on the ankles and top of the feet. These are xanthomas. They are minute tumors containing foam cells, and are the same
types of cells that migrate in the arterial endolhelium and cause atherogenesis. There is no cure, just treatment. The disease affects almost all of the body's functions, and its complexity is such that a cure will be many, many years in the future. I kind of ran away with myself...sorry,,, God bless all,,,,,,Oldguy

 
Old 03-15-2001, 06:17 AM   #5
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chrismth HB User
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Hi Old Guy:

I would really wonder about any doctor who ignored triglycerides at a level of 1,000.
Even the cardiologists I saw, who were lax in my opinion, said trigs of 400 was "too high".

Have you heard of anyone being treated with one of these diabetes drugs (assuming they show signs of impaired glucose tolerance) and their lipid and hypertension problems are solved? Can that process you described causing hypertension be reversed, or is the damage done once it happens?

Chris

 
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