Re: Prednisone induced diabetes
I don't know much about prednisone, but I do know it is used in patients who don't produce enough cortisol so I'll assume it has effects similar to cortisol.
Cortisol, prednisone and all Corticosteroids can elevate blood sugars.
I struggled with high cortisol levels mostly due to stress. I struggle most with the symptons in the morning, when cortisol levels are highest. You probably see this at any time becauser the prednisone is always there.
I read a lot about it, experimented, including getting cortisol level measurements and these are my understandings/findings. I am not a Dr so may have this all wrong, but I have read this many times and from many sources and it correlates to what I see in my body and glucose levels
Cortisol causes insulin resistance. In the morning if I eat 15g of carbs my levels go MUCH higher than if I eat those 15g at night. This is because cortisole levels are highest in the morning. I show the least insulin resistance at 4PM when they are the lowest. When they measured my levels, they charted the cortisol levels throughout the day and 4PM was the lowest.
One form of insulin resitance is hepatic insulin resistance (hepatic being of the liver). The liver does not sense insulin presence, therefore beleives glucose levels are low, therefore pumps out more glucose. This would explain your rise in glucose levels when you went for a walk. When your heart beat starts to rise, it signals to the liver excercise hast started, hence glucose is needed, so produce it. If it got high, insulin would be present, the liver would detect it and stop producing glucose. But your liver may not be detecting, hence continue to produce glucose.
Diabetics can see their glucose levels rise after excercise. I am type II and if I do intense excercise in the morning my levels sometimes rise
Can this explain numbers in the 200 and 300s. Once I was under severe stress. I am talking severe. I woke up in the middle of the night panicked. Just for the hell of it, I tested my BS. It was 216. For me this is an absolutely crazy number. My 1ac is low 5, this was a freak incident, completely induced from stress. This is what caused me to research this. When I learned the effects of cortisol, I found ways to reduce it and it really helped my glucose levels.
Do some research, this may give you a start. Corticosteroid, hepatic insulin resistance are words you can use to research. Good luck
PS : You can always use candy and potatoes to bring those levels down (just kidding)
Last edited by itotito; 09-08-2008 at 07:20 AM.