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Old 06-11-2009, 01:42 PM   #1
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Post Fasting plasma glucose levels in the high normal range

Came upon this article:

Normal Fasting Plasma Glucose Levels and Type 2 Diabetes in Young Men
Amir Tirosh, M.D., Ph.D., Iris Shai, R.D., Ph.D., Dorit Tekes-Manova, M.D., Eran Israeli, M.D., David Pereg, M.D., Tzippora Shochat, M.Sc., Ilan Kochba, M.D., Assaf Rudich, M.D., Ph.D., for the Israeli Diabetes Research Group

Basically, it found that, even within the "normal" (not pre-diabetic or diabetic) range, higher fasting plasma glucose levels indicate increased risk of developing type 2 diabetes. The highest quintile, with fasting plasma glucose levels of 95 to 99 mg/dl, had a 2.84 times risk of developing diabetes compared the lowest quintile, with fasting plasma glucose levels of 50 to 81 mg/dl.

It also noted that the hazard ratio between the highest and lowest quintiles was 1.73 for those with BMI < 25, but 3.78 for those with BMI >= 25. The hazard ratio was also higher among those with triglycerides >= 150 mg/dl.

Thoughts?

 
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