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Old 04-11-2010, 07:45 PM   #1
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Lantus causing headaches?

Hi All-

I was wondering if anyone here is taking Lantus. I was able to drop all but one of my oral meds by switching to Lantus, but I have a major headache all the time. At first, I thought it might be the major pollen hit in my area, but can't be sure.


Old 04-12-2010, 11:11 AM   #2
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Re: Lantus causing headaches?

whacked? how are your BG readings? Are they too low? Headaches are an effect of low sugars. You could also be on too much of it or maybe it's your body telling you that it's not the right insulin for you. Talk to your doctor about it. It shouldn't cause headaches.

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Old 04-12-2010, 07:32 PM   #3
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Re: Lantus causing headaches?


That's just one thing I'm investigating. I run about 120 in the mornings, and I checked my BG before dinner tonight and it was 131. I cut back my Lantus a few units to see if I can get a pattern.

I'll be checking with the MD if this doesn't go away in a week.


Old 04-29-2010, 06:34 PM   #4
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Re: Lantus causing headaches?

It's possible. There are so many things we do not know about synthetic insulin, especially lantus. Lantus is a liquid when injected, but precipitates in the muscles immediately. As the pH changes over time in the muscles, the lantus resuspends, absorbs, and is distributed throughout the day. Because there is an initial equilibrium "boundary" reached (around 3 hours), there will be a slight "peak" in activity at or near this time. The point is that the soldified substance in the muscles is likely foreign to the body, and your guess is as good as mine as to how the body responds. When the liver processes the lantus, there has to be some degree of methylation as well, and I suppose down the road "metabolites" of these compounds could cause headache. Again, just speculative.

As a side note, I like lantus and I think it does a good job. But because of the varying pH's in the muscles at various times of the day, you will notice "dead times" and sort of "peak times", but not nearly as drastic as NPH or Regular insulins. If I were you, I would recommend really researching this topic and seeing if others notice similar side effects.

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