A few months ago my new doctor put me on a new medicine called GLIMEPIRIDE 4mg twice daily.Last month my A1C was 6.1,down from 12.This month it was 5.7.I have been off of insulin for 2 months now.I still take METFORMIN 1000 mg twice daily too.He's talking about taking me off of the METFORMIN.My blood sugar numbers are 80-130 in the morning and 70-100 in the evening. I'm still quite heavy but i'm working on that too.My diet is around 1000-1500 calories a day.I can't exercise like I want,due to a broke ankle,but that will be operated on soon.I have cut out ALL sweets and salts in my diet and am feeling better all the time.
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The anticipation of death is worse then death itself!
Be careful. The drug you are taking is a sulfonylureas and this forces your pancreas to produce more insulin. Some believe that it more rapidly burns out your pancreas necessitating the introduction of insulin injections. This is why met is now preferred by most docs.
I agree with what Cora said about the glimepiride. While it's a good thing that your A1c is down, the less glimepiride you take, the better.
Back in the days when all that was available for T2's were the sulfonylureas, both my brother and I (both diagnosed in our 30's) ended up on insulin quite quickly because the sylufonylureas burned out what was left of our beta cells.
Obviously, 12 was WAY too high for an A1c, but anything at 6.5 or less is incredibly excellent for a diabetic, so perhaps the best course would be to stay on the metformin and maybe decrease the glimepiride a bit. And if you're losing weight, that will also help. Either way, I definitely wouldn't eliminate the metformin as you are most likely quite insulin resistant and if you eliminate the metformin, you'll need more glimepiride and you will end up needing insulin sooner, not later.
UPDATE I moved back to my home state because FL would not give me the help I needed to heal my fractured ankle. I am now going to a charity hospital who has qualified me for the free help I need. The doctors have cut back my GLIMIPIRIDE to once a day because my BG numbers were getting too low. They are anywhere from 60-100 now,morning or evening. I see the orthapedic surgeon for the first time tomorrow morning to find out what they will do to my ankle. You can say i'm nervous but excited too. BTW,my A1C was 5.8 two weeks ago.
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The anticipation of death is worse then death itself!
My A1C numbers 
