Never tried slippery elm, but thought I would tell you my experience with the PPI,,, my doc says that nexium and prilosec are the same thing. Originally my doc put me on 20mg prilosec,, I just refused to take it like I should, because it made me feel miserable. After a few years of misery I finally went to a doc who said it comes in a lower dose lets try that,,, so they put me on 10 mg. prilosec and I do just splendidly on that. Several doctors since have said "10 mg prilosec? I think you mean 20 they don't make 10's",,,,,, but I am here to tell you they DO make a smaller dose and it MIGHT be just the ticket for him as it was for me.